Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC32
  • Mouse genes Lrrc32
  • Rat genes Lrrc32
  • Zfish genes lrrc32
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc32

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRRC32	IPI	UniProtKB:P01137	Human	PMID:19651619
Molecular Function	GO:0005515	protein binding	LRRC32	IPI	UniProtKB:Q86VI4	Human	PMID:26126825
Molecular Function	GO:0005515	protein binding	LRRC32	IPI	UniProtKB:P01137	Human	PMID:28514442
Molecular Function	GO:0050431	transforming growth factor beta binding	LRRC32	IPI	UniProtKB:P01137	Human	PMID:19651619
Molecular Function	GO:0050431	transforming growth factor beta binding	LRRC32	IPI	UniProtKB:P61812	Human	PMID:19651619
Molecular Function	GO:0050431	transforming growth factor beta binding	LRRC32	IDA		Human	PMID:22278742
Molecular Function	GO:0050431	transforming growth factor beta binding	Lrrc32	IPI	UniProtKB:P17125	Mouse	MGI:MGI:5920420|PMID:28912269
Cellular Component	GO:0009986	cell surface	LRRC32	IDA		Human	PMID:19651619
Cellular Component	GO:0009986	cell surface	LRRC32	IDA		Human	PMID:19750484
Cellular Component	GO:0005654	nucleoplasm	LRRC32	IDA		Human	GO_REF:0000052
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	Lrrc32	IDA		Mouse	PMID:18628982
Biological Process	GO:0001818	negative regulation of cytokine production	Lrrc32	IDA		Mouse	PMID:18628982
Biological Process	GO:0030168	platelet activation	lrrc32	IMP	ZFIN:ZDB-MRPHLNO-090630-14	Zfish	PMID:19109564
Biological Process	GO:0030168	platelet activation	lrrc32	IMP	ZFIN:ZDB-MRPHLNO-090630-15	Zfish	PMID:19109564
Biological Process	GO:0010628	positive regulation of gene expression	Lrrc32	IDA		Mouse	PMID:18628982
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	LRRC32	IDA		Human	PMID:19651619
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	LRRC32	IDA		Human	PMID:19750484
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	LRRC32	IDA		Human	PMID:22278742
Biological Process	GO:1901398	regulation of transforming growth factor beta3 activation	Lrrc32	IDA		Mouse	MGI:MGI:5920420|PMID:28912269
Biological Process	GO:0062009	secondary palate development	Lrrc32	IMP		Mouse	MGI:MGI:5920420|PMID:28912269
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	LRRC32	IDA		Human	PMID:19750484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern