Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC52
  • Mouse genes Lrrc52
  • Rat genes Lrrc52
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc52

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0099104	potassium channel activator activity	LRRC52	IDA		Human	PMID:22547800
Molecular Function	GO:0005267	potassium channel activity	Lrrc52	IMP	MGI:MGI:4881116	Mouse	PMID:25675513
Molecular Function	GO:0005515	protein binding	LRRC52	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0044325	transmembrane transporter binding	LRRC52	IPI	UniProtKB:Q12791	Human	PMID:22547800
Molecular Function	GO:0005249	voltage-gated potassium channel activity	LRRC52	IDA		Human	PMID:22547800
Cellular Component	GO:0008076	voltage-gated potassium channel complex	LRRC52	IDA		Human	PMID:22547800
Biological Process	GO:0051649	establishment of localization in cell	Lrrc52	IMP	MGI:MGI:4881116	Mouse	PMID:25675513
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	LRRC52	IDA		Human	PMID:22547800
Biological Process	GO:0071805	potassium ion transmembrane transport	LRRC52	IDA		Human	PMID:22547800
Biological Process	GO:0006813	potassium ion transport	Lrrc52	IMP	MGI:MGI:4881116	Mouse	PMID:25675513
Biological Process	GO:0022414	reproductive process	Lrrc52	IMP	MGI:MGI:4881116	Mouse	PMID:25675513

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern