Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRFIP1
  • Mouse genes Lrrfip1
  • Rat genes Lrrfip1
  • Zfish genes lrrfip1a,lrrfip1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrfip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	LRRFIP1	HDA		Human	PMID:25468996
Molecular Function	GO:0003677	DNA binding	LRRFIP1	IDA		Human	PMID:23099021
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	LRRFIP1	IDA		Human	PMID:14522076
Molecular Function	GO:0005515	protein binding	LRRFIP1	IPI	UniProtKB:Q13045	Human	PMID:10366446
Molecular Function	GO:0005515	protein binding	LRRFIP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LRRFIP1	IPI	UniProtKB:Q13045	Human	PMID:9671805
Molecular Function	GO:0005515	protein binding	Lrrfip1	IPI	UniProtKB:O42486|UniProtKB:Q925T6	Mouse	MGI:MGI:3843430|PMID:16990252
Molecular Function	GO:0005515	protein binding	Lrrfip1	IPI	PR:P22366	Mouse	PMID:19265123
Molecular Function	GO:0005515	protein binding	Lrrfip1	IPI	PR:Q9JJ28	Mouse	PMID:19265123
Molecular Function	GO:0042803	protein homodimerization activity	LRRFIP1	IDA		Human	PMID:23099021
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	LRRFIP1	IDA		Human	PMID:14522076
Cellular Component	GO:0005829	cytosol	LRRFIP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	LRRFIP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	LRRFIP1	IDA		Human	PMID:14522076
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip1	IDA		Mouse	PMID:19265123
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip1	IGI	MGI:MGI:96824	Mouse	PMID:19265123

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern