Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRSAM1
  • Mouse genes Lrsam1
  • Rat genes Lrsam1
  • Zfish genes lrsam1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrsam1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q61187	Human	PMID:15256501
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q99816	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q99816	Human	PMID:18077552
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P61088	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q99816	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P61088	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q13137	Human	PMID:23245322
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P61088	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q99816	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q9BUL5	Human	PMID:25484098
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P56959	Human	PMID:27615052
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q16204	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q6GPH4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q99816	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q9H898-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:Q9NPF5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRSAM1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0061630	ubiquitin protein ligase activity	LRSAM1	IDA		Human	PMID:23245322
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	LRSAM1	IDA		Human	PMID:15256501
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	LRSAM1	IDA		Human	PMID:18077552
Cellular Component	GO:0005737	cytoplasm	LRSAM1	IDA		Human	PMID:15256501
Cellular Component	GO:0005737	cytoplasm	LRSAM1	IDA		Human	PMID:18077552
Cellular Component	GO:0005829	cytosol	LRSAM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	LRSAM1	IDA		Human	PMID:15256501
Biological Process	GO:0060218	hematopoietic stem cell differentiation	lrsam1	IMP	ZFIN:ZDB-MRPHLNO-170127-1	Zfish	PMID:27797851
Biological Process	GO:0045806	negative regulation of endocytosis	LRSAM1	IMP		Human	PMID:15256501
Biological Process	GO:0048666	neuron development	lrsam1	IMP	ZFIN:ZDB-MRPHLNO-120125-4	Zfish	PMID:22012984
Biological Process	GO:0048666	neuron development	lrsam1	IMP	ZFIN:ZDB-MRPHLNO-120125-3	Zfish	PMID:22012984
Biological Process	GO:2000786	positive regulation of autophagosome assembly	LRSAM1	IMP		Human	PMID:25484098
Biological Process	GO:1904417	positive regulation of xenophagy	LRSAM1	IMP		Human	PMID:23245322
Biological Process	GO:0051865	protein autoubiquitination	LRSAM1	IDA		Human	PMID:15256501
Biological Process	GO:0051865	protein autoubiquitination	LRSAM1	IDA		Human	PMID:23245322
Biological Process	GO:0030163	protein catabolic process	LRSAM1	IMP		Human	PMID:18077552
Biological Process	GO:0000209	protein polyubiquitination	LRSAM1	IDA		Human	PMID:18077552
Biological Process	GO:0070086	ubiquitin-dependent endocytosis	LRSAM1	IDA		Human	PMID:15256501
Biological Process	GO:0046755	viral budding	LRSAM1	IMP		Human	PMID:15256501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern