Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTB4R2
  • Mouse genes Ltb4r2
  • Rat genes Ltb4r2
  • Zfish genes ltb4r2a,ltb4r2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltb4r2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	ltb4r2b	IDA		Zfish	PMID:25738285
Molecular Function	GO:0004930	G protein-coupled receptor activity	ltb4r2a	IDA		Zfish	PMID:25738285
Molecular Function	GO:0001632	leukotriene B4 receptor activity	Ltb4r2	IDA		Mouse	PMID:15866883
Cellular Component	GO:0009986	cell surface	ltb4r2b	IDA		Zfish	PMID:25738285
Cellular Component	GO:0009986	cell surface	ltb4r2a	IDA		Zfish	PMID:25738285
Cellular Component	GO:0016020	membrane	LTB4R2	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Ltb4r2	IDA		Mouse	PMID:15866883
Cellular Component	GO:0005654	nucleoplasm	LTB4R2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	LTB4R2	IDA		Human	GO_REF:0000052
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ltb4r2b	IDA		Zfish	PMID:25738285|ZFIN:ZDB-PUB-150305-1
Biological Process	GO:0051546	keratinocyte migration	Ltb4r2	IDA		Mouse	PMID:15866883
Biological Process	GO:0007165	signal transduction	Ltb4r2	IDA		Mouse	PMID:15866883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern