Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTBP1
  • Mouse genes Ltbp1
  • Rat genes Ltbp1
  • Zfish genes ltbp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050436	microfibril binding	LTBP1	IDA		Human	PMID:12429738
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:P35555	Human	PMID:12429738
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:P35556	Human	PMID:12429738
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:P35555,UniProtKB:Q14767	Human	PMID:17293099
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:Q86TH1	Human	PMID:18677313
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:P35555	Human	PMID:19349279
Molecular Function	GO:0005515	protein binding	LTBP1	IPI	UniProtKB:O95967	Human	PMID:27339457
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P01137	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P10600	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P61812	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P01137	Human	PMID:18672106
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P01137	Human	PMID:2022183
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P61812	Human	PMID:2022183
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P01137	Human	PMID:8617200
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP1	IPI	UniProtKB:P61812	Human	PMID:8617200
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	IDA		Human	PMID:16157329
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ltbp1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ltbp1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ltbp1	IDA		Rat	PMID:9766531|RGD:10412061
Cellular Component	GO:0005737	cytoplasm	Ltbp1	IDA		Rat	PMID:9828223|RGD:10412305
Cellular Component	GO:0030425	dendrite	Ltbp1	IDA		Rat	PMID:11720783|RGD:10412057
Cellular Component	GO:0031012	extracellular matrix	LTBP1	IDA		Human	PMID:8617200
Cellular Component	GO:0031012	extracellular matrix	Ltbp1	IDA		Mouse	PMID:9008713
Cellular Component	GO:0005576	extracellular region	LTBP1	HDA		Human	PMID:27068509
Cellular Component	GO:0038045	large latent transforming growth factor-beta complex	Ltbp1	IDA		Rat	PMID:11907708|RGD:10412304
Cellular Component	GO:0001527	microfibril	LTBP1	IDA		Human	PMID:12429738
Cellular Component	GO:0001527	microfibril	Ltbp1	IDA		Mouse	MGI:MGI:4352793|PMID:19349279
Cellular Component	GO:0005739	mitochondrion	Ltbp1	IDA		Rat	PMID:9828223|RGD:10412305
Cellular Component	GO:0043025	neuronal cell body	Ltbp1	IDA		Rat	PMID:11720783|RGD:10412057
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ltbp1	IDA		Rat	PMID:9828223|RGD:10412305
Cellular Component	GO:0032991	protein-containing complex	LTBP1	IDA		Human	PMID:12429738
Biological Process	GO:0035904	aorta development	Ltbp1	IMP		Mouse	PMID:25807483
Biological Process	GO:0030282	bone mineralization	ltbp1	IMP	ZFIN:ZDB-GENO-221103-2	Zfish	PMID:33991472
Biological Process	GO:0060349	bone morphogenesis	ltbp1	IMP	ZFIN:ZDB-GENO-221103-3	Zfish	PMID:33991472
Biological Process	GO:0060349	bone morphogenesis	ltbp1	IMP	ZFIN:ZDB-GENO-221103-2	Zfish	PMID:33991472
Biological Process	GO:0071260	cellular response to mechanical stimulus	Ltbp1	IEP		Rat	PMID:9607192|RGD:10412058
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Ltbp1	IEP		Rat	PMID:15880704|RGD:10412056
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Ltbp1	IEP		Rat	PMID:14708940|RGD:10412060
Biological Process	GO:0071305	cellular response to vitamin D	Ltbp1	IEP		Rat	PMID:10025676|RGD:10412059
Biological Process	GO:0030199	collagen fibril organization	ltbp1	IMP	ZFIN:ZDB-GENO-221103-2	Zfish	PMID:33991472
Biological Process	GO:0030199	collagen fibril organization	ltbp1	IMP	ZFIN:ZDB-GENO-221103-3	Zfish	PMID:33991472
Biological Process	GO:0060976	coronary vasculature development	Ltbp1	IMP		Mouse	PMID:25807483
Biological Process	GO:1904888	cranial skeletal system development	ltbp1	IMP	ZFIN:ZDB-MRPHLNO-221109-1	Zfish	PMID:35320333
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Ltbp1	IMP		Rat	PMID:9607192|RGD:10412058
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	LTBP1	IDA		Human	PMID:2022183
Biological Process	GO:1901388	regulation of transforming growth factor beta activation	LTBP1	IDA		Human	PMID:8617200
Biological Process	GO:0035583	sequestering of TGFbeta in extracellular matrix	LTBP1	IDA		Human	PMID:2022183
Biological Process	GO:0035583	sequestering of TGFbeta in extracellular matrix	LTBP1	IDA		Human	PMID:8617200
Biological Process	GO:0003281	ventricular septum development	Ltbp1	IMP		Mouse	PMID:25807483
Biological Process	GO:0042060	wound healing	Ltbp1	IEP		Rat	PMID:10934147|RGD:2315084

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern