Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTBP3
  • Mouse genes Ltbp3
  • Rat genes Ltbp3
  • Zfish genes ltbp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltbp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LTBP3	IPI	UniProtKB:O95967	Human	PMID:27339457
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP3	IPI	UniProtKB:P01137	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP3	IPI	UniProtKB:P10600	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP3	IPI	UniProtKB:P61812	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP3	IPI	UniProtKB:P01137	Human	PMID:18672106
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP3	IDA		Human	PMID:16157329
Cellular Component	GO:0070062	extracellular exosome	LTBP3	HDA		Human	PMID:19199708
Cellular Component	GO:0005576	extracellular region	LTBP3	HDA		Human	PMID:27068509
Cellular Component	GO:0005576	extracellular region	Ltbp3	IDA		Mouse	PMID:7730318
Biological Process	GO:0030282	bone mineralization	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0060349	bone morphogenesis	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0060349	bone morphogenesis	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:20530870
Biological Process	GO:0046849	bone remodeling	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0003208	cardiac ventricle morphogenesis	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-110801-4	Zfish	PMID:21623370
Biological Process	GO:0048469	cell maturation	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-170327-1	Zfish	PMID:28049660
Biological Process	GO:0002062	chondrocyte differentiation	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0014831	gastro-intestinal system smooth muscle contraction	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-170327-1	Zfish	PMID:28049660
Biological Process	GO:0060430	lung saccule development	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:16049328
Biological Process	GO:0030502	negative regulation of bone mineralization	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:11790802
Biological Process	GO:0003151	outflow tract morphogenesis	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-110801-4	Zfish	PMID:21623370
Biological Process	GO:0045780	positive regulation of bone resorption	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:15878314
Biological Process	GO:2000741	positive regulation of mesenchymal stem cell differentiation	LTBP3	IMP		Human	PMID:18672106
Biological Process	GO:1902462	positive regulation of mesenchymal stem cell proliferation	LTBP3	IMP		Human	PMID:18672106
Biological Process	GO:1905899	regulation of smooth muscle tissue development	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-110801-4	Zfish	PMID:28049660
Biological Process	GO:0001501	skeletal system development	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:12379497
Biological Process	GO:0051145	smooth muscle cell differentiation	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-170327-3	Zfish	PMID:28049660
Biological Process	GO:0048659	smooth muscle cell proliferation	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-170327-3	Zfish	PMID:28049660
Biological Process	GO:0090130	tissue migration	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-170327-1	Zfish	PMID:28049660
Biological Process	GO:0036363	transforming growth factor beta activation	LTBP3	IMP		Human	PMID:18672106
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Ltbp3	IPI	PR:P04202	Mouse	PMID:7730318
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Ltbp3	IMP	MGI:MGI:2180017	Mouse	PMID:12379497
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ltbp3	IMP	ZFIN:ZDB-MRPHLNO-110801-4	Zfish	PMID:28049660

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern