Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LUM
  • Mouse genes Lum
  • Rat genes Lum
  • Zfish genes lum
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lum

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	LUM	IDA		Human	PMID:10892350
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:P50281	Human	PMID:25304424
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LUM	IPI	UniProtKB:Q92993	Human	PMID:32814053
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LUM	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LUM	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LUM	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LUM	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lum	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lum	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	LUM	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Lum	IDA		Mouse	PMID:12128073
Cellular Component	GO:0031012	extracellular matrix	Lum	IDA		Rat	PMID:11348051|RGD:1582122
Cellular Component	GO:0005576	extracellular region	LUM	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	LUM	HDA		Human	PMID:20551380
Cellular Component	GO:0005583	fibrillar collagen trimer	LUM	IDA		Human	PMID:10734230
Biological Process	GO:0048593	camera-type eye morphogenesis	lum	IMP	ZFIN:ZDB-MRPHLNO-100915-1	Zfish	PMID:33691248
Biological Process	GO:0051216	cartilage development	Lum	IEP		Rat	PMID:19746167|RGD:2317685
Biological Process	GO:0030199	collagen fibril organization	lum	IMP	ZFIN:ZDB-MRPHLNO-100915-1	Zfish	PMID:20551313
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	lum	IMP	ZFIN:ZDB-MRPHLNO-100915-1	Zfish	PMID:20551313
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Lum	IDA		Mouse	PMID:15849191
Biological Process	GO:0032914	positive regulation of transforming growth factor beta1 production	Lum	IMP		Mouse	MGI:MGI:5295830|PMID:21931815
Biological Process	GO:0070848	response to growth factor	Lum	IEP		Rat	PMID:18482974|RGD:2317692
Biological Process	GO:0014070	response to organic cyclic compound	Lum	IEP		Rat	PMID:18602130|RGD:2303788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern