Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LY96
  • Mouse genes Ly96
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ly96

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001875	lipopolysaccharide immune receptor activity	LY96	IDA		Human	PMID:19252480
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206	Human	PMID:15728506
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206	Human	PMID:17803912
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206-1	Human	PMID:19060881
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:P49278	Human	PMID:19060881
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206	Human	PMID:19252480
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206-1	Human	PMID:19252480
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206	Human	PMID:20547845
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206-1	Human	PMID:22474354
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:O00206-1	Human	PMID:22532668
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:P80188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LY96	IPI	UniProtKB:Q14696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ly96	IPI	UniProtKB:Q9QUK6	Mouse	MGI:MGI:5426338|PMID:22532668
Molecular Function	GO:0005515	protein binding	Ly96	IPI	UniProtKB:Q9QUK6	Mouse	MGI:MGI:5914828|PMID:21857663
Molecular Function	GO:0005515	protein binding	Ly96	IPI	UniProtKB:Q9QUK6	Mouse	MGI:MGI:3763315|PMID:17803912
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	LY96	IDA		Human	PMID:11274165
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	LY96	IDA		Human	PMID:19252480
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	Ly96	IDA		Mouse	MGI:MGI:5645195|PMID:24380872
Cellular Component	GO:0005886	plasma membrane	LY96	IDA		Human	PMID:11274165
Cellular Component	GO:0043235	receptor complex	LY96	IPI		Human	PMID:19252480
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Ly96	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0032497	detection of lipopolysaccharide	LY96	IDA		Human	PMID:19252480
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly96	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly96	IDA		Mouse	PMID:10880523
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly96	IGI	MGI:MGI:96824	Mouse	PMID:10880523
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly96	IGI	MGI:MGI:1194924	Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly96	IGI	MGI:MGI:96824	Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly96	IGI	MGI:MGI:1194924	Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly96	IDA		Mouse	PMID:10880523
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Ly96	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0032496	response to lipopolysaccharide	LY96	IDA		Human	PMID:12594207
Biological Process	GO:0032496	response to lipopolysaccharide	LY96	IDA		Human	PMID:14607928
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	Ly96	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0002224	toll-like receptor signaling pathway	LY96	IDA		Human	PMID:14607928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern