Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYAR
  • Mouse genes Lyar
  • Rat genes Lyar
  • Zfish genes lyar
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lyar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	LYAR	IDA		Human	PMID:25092918
Molecular Function	GO:0140297	DNA-binding transcription factor binding	LYAR	IPI	UniProtKB:Q14653	Human	PMID:31413131
Molecular Function	GO:0042802	identical protein binding	LYAR	IPI	UniProtKB:Q9NX58	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:O75569	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:O14744	Human	PMID:25092918
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:O75569	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q8N7W2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:A0A142I5B9	Human	PMID:30177828
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:O75569	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q9H190	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q8N9Q2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:P0DTC9	Human	PMID:34029587
Molecular Function	GO:0005515	protein binding	LYAR	IPI	UniProtKB:P0DTC9	Human	PMID:34578187
Molecular Function	GO:0003723	RNA binding	LYAR	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	LYAR	HDA		Human	PMID:22681889
Molecular Function	GO:0140416	transcription regulator inhibitor activity	LYAR	IDA		Human	PMID:31413131
Cellular Component	GO:0005730	nucleolus	LYAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	LYAR	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005730	nucleolus	LYAR	IDA		Human	PMID:24495227
Cellular Component	GO:0005730	nucleolus	LYAR	IDA		Human	PMID:31413131
Cellular Component	GO:0005730	nucleolus	LYAR	IDA		Human	PMID:31504794
Cellular Component	GO:0005730	nucleolus	Lyar	IDA		Mouse	PMID:8491376
Cellular Component	GO:0005654	nucleoplasm	LYAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	LYAR	IDA		Human	PMID:22720776
Cellular Component	GO:0005634	nucleus	LYAR	IDA		Human	PMID:25092918
Cellular Component	GO:0001750	photoreceptor outer segment	Lyar	IDA		Mouse	MGI:MGI:6107438|PMID:25735755
Biological Process	GO:0048821	erythrocyte development	LYAR	IMP		Human	PMID:25092918
Biological Process	GO:0045824	negative regulation of innate immune response	LYAR	IDA		Human	PMID:31413131
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	LYAR	IMP		Human	PMID:25092918
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	LYAR	IDA		Human	PMID:31413131
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Lyar	IMP		Mouse	MGI:MGI:6107358|PMID:25092918
Biological Process	GO:0050766	positive regulation of phagocytosis	Lyar	IDA		Mouse	MGI:MGI:6107438|PMID:25735755
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	LYAR	IDA		Human	PMID:31504794
Biological Process	GO:0006364	rRNA processing	LYAR	IMP		Human	PMID:24495227

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern