Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYST
  • Mouse genes Lyst
  • Rat genes Lyst
  • Zfish genes lyst
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lyst

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:O14964	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:O43281	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P0DP23	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P0DP24	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P0DP25	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P11474	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P19429	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P27348	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P31946	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P52272	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P54259	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:P67870	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q14974	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q8N137	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q92665	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q93074	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q96K83	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q9HC77	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q9NRX2	Human	PMID:11984006
Molecular Function	GO:0005515	protein binding	LYST	IPI	UniProtKB:Q9UBB5	Human	PMID:11984006
Cellular Component	GO:0005829	cytosol	Lyst	IDA		Mouse	PMID:9368050
Cellular Component	GO:0015630	microtubule cytoskeleton	LYST	IDA		Human	PMID:9606205
Biological Process	GO:0007596	blood coagulation	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:6696991
Biological Process	GO:0042742	defense response to bacterium	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4589319
Biological Process	GO:0042742	defense response to bacterium	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:7988496
Biological Process	GO:0042742	defense response to bacterium	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4601767
Biological Process	GO:0042832	defense response to protozoan	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:6218091
Biological Process	GO:0051607	defense response to virus	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:6272291
Biological Process	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	LYST	IMP		Human	PMID:9606205
Biological Process	GO:0071621	granulocyte chemotaxis	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4589319
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4697831
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855969	Mouse	PMID:9368050
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:6170520
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:1113502
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:9368050
Biological Process	GO:0007040	lysosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4031470
Biological Process	GO:0033364	mast cell secretory granule organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:624833
Biological Process	GO:0032438	melanosome organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4634048
Biological Process	GO:0032438	melanosome organization	Lyst	IMP	MGI:MGI:3620573	Mouse	PMID:16518687
Biological Process	GO:0007017	microtubule-based process	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:187062
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	LYST	IMP		Human	PMID:10648412
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	LYST	IMP		Human	PMID:6154765
Biological Process	GO:0002446	neutrophil mediated immunity	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:7988496
Biological Process	GO:0055091	phospholipid homeostasis	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:580786
Biological Process	GO:0006644	phospholipid metabolic process	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:580786
Biological Process	GO:0048753	pigment granule organization	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:1278263
Biological Process	GO:0043473	pigmentation	LYST	IMP		Human	PMID:10648412
Biological Process	GO:0043473	pigmentation	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:2513223
Biological Process	GO:0043473	pigmentation	Lyst	IMP	MGI:MGI:2660913	Mouse	PMID:13943454
Biological Process	GO:0043473	pigmentation	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:4031470
Biological Process	GO:0043473	pigmentation	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:7089489
Biological Process	GO:0043473	pigmentation	Lyst	IMP		Rat	PMID:12638234|RGD:1302441
Biological Process	GO:0032816	positive regulation of natural killer cell activation	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:7089489
Biological Process	GO:0009410	response to xenobiotic stimulus	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:2513223
Biological Process	GO:0033299	secretion of lysosomal enzymes	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:408
Biological Process	GO:0033299	secretion of lysosomal enzymes	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:7089489
Biological Process	GO:0002456	T cell mediated immunity	Lyst	IMP	MGI:MGI:1855968	Mouse	PMID:6977094

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern