Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes M6PR
  • Mouse genes M6pr
  • Rat genes M6pr
  • Zfish genes m6pr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set M6pr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005537	mannose binding	m6pr	IDA		Zfish	PMID:16362416
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q96QK1	Human	PMID:27385586
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q86UP2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q9NZG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:Q9UNI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	M6PR	IPI	UniProtKB:P21964-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	M6pr	IPI	UniProtKB:P07602	Mouse	MGI:MGI:5701557|PMID:26370502
Molecular Function	GO:0019904	protein domain specific binding	m6pr	IPI	UniProtKB:Q9UJY5	Zfish	PMID:16362416
Molecular Function	GO:1905394	retromer complex binding	M6PR	IMP		Human	PMID:27385586
Cellular Component	GO:0005768	endosome	M6PR	IDA		Human	PMID:15078902
Cellular Component	GO:0005770	late endosome	M6pr	IDA		Mouse	PMID:12388596
Cellular Component	GO:0016020	membrane	M6PR	HDA		Human	PMID:19946888
Cellular Component	GO:0048471	perinuclear region of cytoplasm	M6PR	IDA		Human	PMID:16154903
Cellular Component	GO:0048471	perinuclear region of cytoplasm	M6PR	IDA		Human	PMID:27385586
Cellular Component	GO:0005802	trans-Golgi network	m6pr	IDA		Zfish	PMID:16362416
Biological Process	GO:0007041	lysosomal transport	M6pr	IDA		Mouse	MGI:MGI:5701557|PMID:26370502
Biological Process	GO:0006622	protein targeting to lysosome	m6pr	IMP		Zfish	PMID:16362416
Biological Process	GO:0033299	secretion of lysosomal enzymes	M6pr	IDA		Mouse	PMID:19710420

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern