Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MACIR
  • Mouse genes Macir
  • Rat genes Macir
  • Zfish genes macir
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Macir

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:A6NIH7	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q13432	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q96B26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MACIR	IPI	UniProtKB:Q92993	Human	PMID:32814053
Cellular Component	GO:0035869	ciliary transition zone	MACIR	IDA		Human	PMID:22085962
Cellular Component	GO:0005737	cytoplasm	MACIR	IDA		Human	PMID:22085962
Cellular Component	GO:0005737	cytoplasm	MACIR	IDA		Human	PMID:30659109
Biological Process	GO:0060271	cilium assembly	macir	IMP		Zfish	PMID:22085962|ZFIN:ZDB-PUB-120416-1
Biological Process	GO:0002534	cytokine production involved in inflammatory response	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0010631	epithelial cell migration	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0010761	fibroblast migration	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0070121	Kupffer's vesicle development	macir	IMP	ZFIN:ZDB-MRPHLNO-120424-6	Zfish	PMID:22085962
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0010633	negative regulation of epithelial cell migration	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0010764	negative regulation of fibroblast migration	Macir	IMP		Mouse	PMID:26316022
Biological Process	GO:0050728	negative regulation of inflammatory response	MACIR	IMP		Human	PMID:30659109
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	macir	IMP	ZFIN:ZDB-MRPHLNO-120424-6	Zfish	PMID:30659109
Biological Process	GO:1905521	regulation of macrophage migration	macir	IMP		Zfish	PMID:30659109|ZFIN:ZDB-PUB-190120-1
Biological Process	GO:0061041	regulation of wound healing	macir	IMP	ZFIN:ZDB-MRPHLNO-120424-6	Zfish	PMID:30659109

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern