Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MACROD2
  • Mouse genes Macrod2
  • Rat genes
  • Zfish genes macrod2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Macrod2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140293	ADP-ribosylglutamate hydrolase activity	MACROD2	IDA		Human	PMID:23474714
Molecular Function	GO:0019213	deacetylase activity	MACROD2	IDA		Human	PMID:21257746
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	MACROD2	IDA		Human	PMID:23474712
Cellular Component	GO:0005730	nucleolus	MACROD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MACROD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MACROD2	IDA		Human	PMID:23474712
Biological Process	GO:0007420	brain development	Macrod2	IEP		Mouse	MGI:MGI:4887328|PMID:17586838
Biological Process	GO:0006974	DNA damage response	MACROD2	IMP		Human	PMID:23474712
Biological Process	GO:0140291	peptidyl-glutamate ADP-deribosylation	MACROD2	IDA		Human	PMID:23474714
Biological Process	GO:0051725	protein de-ADP-ribosylation	MACROD2	IDA		Human	PMID:23474712
Biological Process	GO:0042278	purine nucleoside metabolic process	MACROD2	IDA		Human	PMID:21257746
Biological Process	GO:0009617	response to bacterium	Macrod2	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern