Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mad2l1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAD2L1
- Mouse genes Mad2l1
- Rat genes Mad2l1
- Zfish genes mad2l1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mad2l1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:16525508
Molecular Function	GO:0042802	identical protein binding	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:18022367
Molecular Function	GO:0042802	identical protein binding	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:18318601
Molecular Function	GO:0042802	identical protein binding	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:21041666
Molecular Function	GO:0042802	identical protein binding	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O15205	Human	PMID:10200259
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P78536	Human	PMID:10527948
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:10700282
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:12006501
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:15182668
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:15525512
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y3Q8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:16525508
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:17443180
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:17443180
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:17443186
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:17443186
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:18022367
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:18022368
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:18318601
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:18318601
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:18692475
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q00613	Human	PMID:18794143
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P12270	Human	PMID:18981471
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9-1	Human	PMID:19010891
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9-3	Human	PMID:19010891
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:19143472
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P12270	Human	PMID:19273613
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q14145	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P12270	Human	PMID:20133940
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:20212161
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:20212161
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:20212161
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:20951947
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:21041666
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:21041666
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:21300909
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:21300909
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:21407176
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:21666598
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q562F6	Human	PMID:21666598
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:22000412
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:22340593
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:22493223
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:24581499
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:24581499
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:25383541
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:25383541
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q14145	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y3Q8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O15205	Human	PMID:25422469
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O60566	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:26258632
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P30260	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q12834	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y3Q8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q14145	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:O75140-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:P06213-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q14145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q15013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q7L775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAD2L1	IPI	UniProtKB:Q9Y6D9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Mad2l1	IPI	UniProtKB:Q9NRI5	Mouse	MGI:MGI:6694457\|PMID:29961565
Molecular Function	GO:0005515	protein binding	Mad2l1	IPI	UniProtKB:Q7TSY8	Mouse	MGI:MGI:5508723\|PMID:21666598
Molecular Function	GO:0042803	protein homodimerization activity	MAD2L1	IPI	UniProtKB:Q13257	Human	PMID:18022367
Cellular Component	GO:0005694	chromosome	Mad2l1	IDA		Mouse	PMID:17325031
Cellular Component	GO:0000775	chromosome, centromeric region	Mad2l1	IDA		Mouse	PMID:12355205
Cellular Component	GO:0005737	cytoplasm	Mad2l1	IDA		Mouse	PMID:17504913
Cellular Component	GO:0005829	cytosol	MAD2L1	IDA		Human	PMID:18981471
Cellular Component	GO:0000776	kinetochore	MAD2L1	IDA		Human	PMID:17363900
Cellular Component	GO:0000776	kinetochore	MAD2L1	IDA		Human	PMID:19468067
Cellular Component	GO:0000776	kinetochore	MAD2L1	IDA		Human	PMID:19229290
Cellular Component	GO:0000776	kinetochore	MAD2L1	IDA		Human	PMID:20133940
Cellular Component	GO:0000776	kinetochore	MAD2L1	IDA		Human	PMID:8824189
Cellular Component	GO:0000776	kinetochore	Mad2l1	IDA		Mouse	PMID:19075002
Cellular Component	GO:0000776	kinetochore	Mad2l1	IDA		Mouse	PMID:19376971
Cellular Component	GO:0000776	kinetochore	Mad2l1	IDA		Mouse	PMID:17504913
Cellular Component	GO:0000776	kinetochore	Mad2l1	IDA		Mouse	PMID:10964468
Cellular Component	GO:0033597	mitotic checkpoint complex	MAD2L1	IPI		Human	PMID:27509861
Cellular Component	GO:0072686	mitotic spindle	MAD2L1	IDA		Human	PMID:20133940
Cellular Component	GO:1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	MAD2L1	IPI		Human	PMID:12006501
Cellular Component	GO:1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	Mad2l1	IPI		Mouse	MGI:MGI:6828900\|PMID:12006501
Cellular Component	GO:0044615	nuclear pore nuclear basket	MAD2L1	IDA		Human	PMID:18981471
Cellular Component	GO:0005654	nucleoplasm	MAD2L1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MAD2L1	IDA		Human	PMID:18981471
Cellular Component	GO:0005634	nucleus	MAD2L1	IDA		Human	PMID:19010891
Cellular Component	GO:0005634	nucleus	MAD2L1	IDA		Human	PMID:20870947
Cellular Component	GO:0005634	nucleus	Mad2l1	IDA		Mouse	PMID:26919979
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MAD2L1	IDA		Human	PMID:20870947
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MAD2L1	IDA		Human	PMID:8824189
Cellular Component	GO:0000922	spindle pole	Mad2l1	IDA		Mouse	PMID:17504913
Cellular Component	GO:0000922	spindle pole	Mad2l1	IDA		Mouse	PMID:10964468
Biological Process	GO:0051660	establishment of centrosome localization	MAD2L1	IMP		Human	PMID:23509069
Biological Process	GO:0000132	establishment of mitotic spindle orientation	MAD2L1	IMP		Human	PMID:23509069
Biological Process	GO:0000070	mitotic sister chromatid segregation	Mad2l1	IMP	MGI:MGI:2178781	Mouse	PMID:10892650
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	MAD2L1	IDA		Human	PMID:18981471
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	Mad2l1	IMP	MGI:MGI:2178781	Mouse	PMID:11201745
Biological Process	GO:0043066	negative regulation of apoptotic process	MAD2L1	IMP		Human	PMID:20870947
Biological Process	GO:0043066	negative regulation of apoptotic process	Mad2l1	IMP		Mouse	MGI:MGI:4839685\|PMID:20870947
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	MAD2L1	IMP		Human	PMID:21274008
Biological Process	GO:0042177	negative regulation of protein catabolic process	MAD2L1	IDA		Human	PMID:11459825
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	MAD2L1	IDA		Human	PMID:11459825
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	MAD2L1	IDA		Human	PMID:11535616
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	MAD2L1	IMP		Human	PMID:20870947
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	MAD2L1	IDA		Human	PMID:22898774
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	MAD2L1	IDA		Human	PMID:8824189
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	Mad2l1	IMP		Mouse	MGI:MGI:4839685\|PMID:20870947

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.