Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MADCAM1
  • Mouse genes Madcam1
  • Rat genes Madcam1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Madcam1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098640	integrin binding involved in cell-matrix adhesion	MADCAM1	IDA		Human	PMID:23986478
Biological Process	GO:0007568	aging	Madcam1	IEP		Rat	PMID:14768948|RGD:2311548
Biological Process	GO:0007155	cell adhesion	Madcam1	IDA		Rat	PMID:12859728|RGD:724402
Biological Process	GO:0007160	cell-matrix adhesion	MADCAM1	IDA		Human	PMID:18308860
Biological Process	GO:0034113	heterotypic cell-cell adhesion	MADCAM1	IMP		Human	PMID:18308860
Biological Process	GO:0007229	integrin-mediated signaling pathway	MADCAM1	IDA		Human	PMID:23986478
Biological Process	GO:0030216	keratinocyte differentiation	Madcam1	IMP		Mouse	PMID:12230506
Biological Process	GO:0050900	leukocyte migration	Madcam1	IMP		Mouse	PMID:15484189
Biological Process	GO:0050901	leukocyte tethering or rolling	MADCAM1	IDA		Human	PMID:18308860
Biological Process	GO:0002687	positive regulation of leukocyte migration	Madcam1	IMP		Rat	PMID:14670821|RGD:2311549
Biological Process	GO:0043113	receptor clustering	MADCAM1	IDA		Human	PMID:23986478

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern