Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAEL
  • Mouse genes Mael
  • Rat genes Mael
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mael

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Mael	IPI	UniProtKB:Q99MV2|UniProtKB:Q9D5S1	Mouse	MGI:MGI:5908497|PMID:28254886
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q99MV1	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:P69566	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q9Z0H3	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q9JMB7	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q62141	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q8CDG1	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q8K1H1	Mouse	PMID:16787967
Molecular Function	GO:0005515	protein binding	Mael	IPI	PR:Q61496	Mouse	PMID:16787967
Cellular Component	GO:0030849	autosome	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0000785	chromatin	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0033391	chromatoid body	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0005737	cytoplasm	Mael	IDA		Mouse	PMID:18694567
Cellular Component	GO:0005737	cytoplasm	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0001673	male germ cell nucleus	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0001673	male germ cell nucleus	Mael	IDA		Mouse	PMID:18694567
Cellular Component	GO:0043186	P granule	Mael	IDA		Mouse	PMID:16787967
Cellular Component	GO:0043186	P granule	Mael	IDA		Mouse	PMID:18694567
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Mael	IDA		Mouse	PMID:18694567
Cellular Component	GO:0071547	piP-body	Mael	IDA		Mouse	MGI:MGI:4417983|PMID:20011505
Cellular Component	GO:0001741	XY body	Mael	IDA		Mouse	MGI:MGI:3655410|PMID:16787967
Biological Process	GO:0006915	apoptotic process	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0000902	cell morphogenesis	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0006974	DNA damage response	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0043046	DNA methylation involved in gamete generation	Mael	IMP		Mouse	MGI:MGI:4417983|PMID:20011505
Biological Process	GO:0035234	ectopic germ cell programmed cell death	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0009566	fertilization	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0010467	gene expression	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0007140	male meiotic nuclear division	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0043066	negative regulation of apoptotic process	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0051093	negative regulation of developmental process	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0010629	negative regulation of gene expression	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:2000242	negative regulation of reproductive process	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0034587	piRNA processing	Mael	IMP		Mouse	MGI:MGI:4417983|PMID:20011505
Biological Process	GO:0034587	piRNA processing	Mael	IMP		Mouse	MGI:MGI:3813746|PMID:18694567
Biological Process	GO:0046620	regulation of organ growth	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567
Biological Process	GO:0031047	RNA-mediated gene silencing	Mael	IMP		Mouse	MGI:MGI:3813746|PMID:18694567
Biological Process	GO:0007283	spermatogenesis	Mael	IMP	MGI:MGI:3795667	Mouse	PMID:18694567

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern