Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAF
  • Mouse genes Maf
  • Rat genes Maf
  • Zfish genes mafa,mafb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Maf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Maf	IDA		Mouse	PMID:12381733
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Maf	IDA		Mouse	PMID:19414009
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Maf	IDA		Mouse	PMID:12835653
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Maf	IDA		Rat	PMID:9571165|RGD:1547884
Molecular Function	GO:0003690	double-stranded DNA binding	Maf	IDA		Rat	PMID:9571165|RGD:1547884
Molecular Function	GO:0042802	identical protein binding	MAF	IPI	UniProtKB:O75444	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	MAF	IPI	UniProtKB:O75444	Human	PMID:23661758
Molecular Function	GO:0042802	identical protein binding	Maf	IPI	RGD:3034	Rat	PMID:9571165|RGD:1547884
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:O14867	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:P0C746	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:P18848	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:Q9Y5Q3	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:P18848	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAF	IPI	UniProtKB:Q9Y5Q3	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	Maf	IPI	UniProtKB:Q91ZW3	Mouse	MGI:MGI:3624889|PMID:16675956
Molecular Function	GO:0005515	protein binding	Maf	IPI	PR:Q04887	Mouse	PMID:12381733
Molecular Function	GO:0044877	protein-containing complex binding	Maf	IDA		Rat	PMID:9571165|RGD:1547884
Molecular Function	GO:0043565	sequence-specific DNA binding	Maf	IDA		Mouse	PMID:10603348
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MAF	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Maf	IDA		Mouse	PMID:15249232
Cellular Component	GO:0005634	nucleus	Maf	IDA		Mouse	PMID:15249232
Cellular Component	GO:0005634	nucleus	Maf	IDA		Rat	PMID:15032330|RGD:13204742
Cellular Component	GO:0005634	nucleus	Maf	IDA		Rat	PMID:9038383|RGD:69874
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MAF	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MAF	IPI		Human	PMID:23661758
Biological Process	GO:0048468	cell development	Maf	IMP	MGI:MGI:2148635	Mouse	PMID:10603348
Biological Process	GO:0001816	cytokine production	Maf	IDA		Mouse	PMID:15790681
Biological Process	GO:0048839	inner ear development	Maf	IDA		Mouse	PMID:21795542
Biological Process	GO:0002088	lens development in camera-type eye	Maf	IMP	MGI:MGI:2148635	Mouse	PMID:10603348
Biological Process	GO:0002088	lens development in camera-type eye	Maf	IMP	MGI:MGI:2148636	Mouse	PMID:12835653
Biological Process	GO:0002088	lens development in camera-type eye	Maf	IMP	MGI:MGI:2148637	Mouse	PMID:10383433
Biological Process	GO:0070306	lens fiber cell differentiation	Maf	IMP	MGI:MGI:2148637	Mouse	PMID:10383433
Biological Process	GO:0070306	lens fiber cell differentiation	Maf	IMP	MGI:MGI:2148636	Mouse	PMID:12835653
Biological Process	GO:0030219	megakaryocyte differentiation	MAF	IMP		Human	PMID:25857263
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Maf	IMP	MGI:MGI:2148637	Mouse	PMID:19623612
Biological Process	GO:0010628	positive regulation of gene expression	Maf	IDA		Mouse	PMID:21460847
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Maf	IMP	MGI:MGI:2148635	Mouse	PMID:10603348
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Maf	IDA		Mouse	PMID:12835653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Maf	IDA		Mouse	PMID:12381733
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Maf	IDA		Rat	PMID:9571165|RGD:1547884
Biological Process	GO:0032330	regulation of chondrocyte differentiation	Maf	IMP	MGI:MGI:2148636	Mouse	PMID:14512017
Biological Process	GO:0006355	regulation of DNA-templated transcription	Maf	IMP	MGI:MGI:2148636	Mouse	PMID:10403649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern