Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAFG
  • Mouse genes Mafg
  • Rat genes Mafg
  • Zfish genes mafga,mafgb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mafg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Mafg	IPI	PR:Q60795	Mouse	PMID:14517290
Molecular Function	GO:0003677	DNA binding	Mafg	IDA		Mouse	PMID:12220541
Molecular Function	GO:0003677	DNA binding	mafgb	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	mafgb	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	mafga	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	mafga	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mafg	IDA		Mouse	MGI:MGI:5905273|PMID:15574414
Molecular Function	GO:0003700	DNA-binding transcription factor activity	mafgb	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	mafga	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Molecular Function	GO:0042802	identical protein binding	MAFG	IPI	UniProtKB:O15525	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	MAFG	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:18692475
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:O14867	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:P0C746	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q14494	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9Y4A8	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:O14867	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q14494	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16649	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9BYV9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9NR55	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9ULX9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9Y4A8	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:O14867	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:O14867	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9Y4A8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q14494-2	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q14494:PRO_0000443103	Human	PMID:8932385
Molecular Function	GO:0005515	protein binding	MAFG	IPI	UniProtKB:Q14494:PRO_0000443103	Human	PMID:9421508
Molecular Function	GO:0005515	protein binding	Mafg	IPI	UniProtKB:Q61985:PRO_0000443104	Mouse	MGI:MGI:6107583|PMID:11342101
Molecular Function	GO:0046982	protein heterodimerization activity	mafgb	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	mafgb	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	mafga	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	mafga	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mafg	IDA		Mouse	MGI:MGI:5905273|PMID:15574414
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MAFG	IDA		Human	PMID:28473536
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MAFG	IPI		Human	PMID:23661758
Cellular Component	GO:0005667	transcription regulator complex	mafgb	IDA		Zfish	PMID:15207702
Cellular Component	GO:0005667	transcription regulator complex	mafga	IDA		Zfish	PMID:15207702
Biological Process	GO:0030534	adult behavior	Mafg	IMP	MGI:MGI:2386717	Mouse	PMID:9679061
Biological Process	GO:0001701	in utero embryonic development	Mafg	IGI	MGI:MGI:1858732	Mouse	PMID:15087497
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	mafgb	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	mafga	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Biological Process	GO:0010628	positive regulation of gene expression	Mafg	IGI	UniProtKB:Q60795	Mouse	MGI:MGI:5616326|PMID:14978030
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mafg	IDA		Mouse	MGI:MGI:5905273|PMID:15574414
Biological Process	GO:0042127	regulation of cell population proliferation	Mafg	IMP	MGI:MGI:2386717	Mouse	PMID:9679061
Biological Process	GO:0030641	regulation of cellular pH	Mafg	IDA		Rat	PMID:11583919|RGD:633304
Biological Process	GO:0045604	regulation of epidermal cell differentiation	Mafg	IGI	MGI:MGI:1858732	Mouse	PMID:15087497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern