Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAFK
  • Mouse genes Mafk
  • Rat genes Mafk
  • Zfish genes mafk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mafk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Mafk	IDA		Mouse	PMID:8887638
Molecular Function	GO:0003677	DNA binding	Mafk	IDA		Mouse	PMID:8622968
Molecular Function	GO:0003677	DNA binding	mafk	IDA		Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	mafk	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	mafk	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15654768
Molecular Function	GO:0003677	DNA binding	mafk	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mafk	IDA		Mouse	MGI:MGI:894855|PMID:9240432
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mafk	IDA		Mouse	PMID:8887638
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mafk	IDA		Mouse	PMID:12220541
Molecular Function	GO:0003700	DNA-binding transcription factor activity	mafk	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MAFK	IDA		Human	PMID:9150357
Molecular Function	GO:0005515	protein binding	MAFK	IPI	UniProtKB:Q16236	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAFK	IPI	UniProtKB:Q16236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAFK	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAFK	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	MAFK	IPI	UniProtKB:Q14494:PRO_0000443103	Human	PMID:8932385
Molecular Function	GO:0005515	protein binding	Mafk	IPI	UniProtKB:Q60795	Mouse	MGI:MGI:894855|PMID:9240432
Molecular Function	GO:0005515	protein binding	Mafk	IPI	UniProtKB:P97302	Mouse	MGI:MGI:5927053|PMID:19011633
Molecular Function	GO:0005515	protein binding	Mafk	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529|PMID:20599664
Molecular Function	GO:0005515	protein binding	Mafk	IPI	PR:P97303	Mouse	PMID:8887638
Molecular Function	GO:0005515	protein binding	Mafk	IPI	PR:P97302	Mouse	PMID:8887638
Molecular Function	GO:0046982	protein heterodimerization activity	mafk	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	mafk	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	mafk	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15654768
Molecular Function	GO:0071535	RING-like zinc finger domain binding	Mafk	IPI	RGD:1304892	Rat	PMID:17083329|RGD:2312274
Molecular Function	GO:0043565	sequence-specific DNA binding	MAFK	IDA		Human	PMID:23332764
Molecular Function	GO:0043565	sequence-specific DNA binding	Mafk	IDA		Mouse	MGI:MGI:894855|PMID:9240432
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Mafk	IDA		Mouse	MGI:MGI:894855|PMID:9240432
Molecular Function	GO:0000976	transcription cis-regulatory region binding	mafk	IDA		Zfish	PMID:24652768
Cellular Component	GO:0005654	nucleoplasm	MAFK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mafk	IDA		Mouse	PMID:8887638
Cellular Component	GO:0005667	transcription regulator complex	mafk	IDA		Zfish	PMID:15207702
Biological Process	GO:0006351	DNA-templated transcription	Mafk	IDA		Mouse	MGI:MGI:2387878|PMID:12220541
Biological Process	GO:0006351	DNA-templated transcription	mafk	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MAFK	IDA		Human	PMID:9150357
Biological Process	GO:0007399	nervous system development	Mafk	IDA		Rat	PMID:12388604|RGD:628386
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	mafk	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mafk	IDA		Mouse	PMID:8887638
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mafk	IDA		Mouse	PMID:12220541
Biological Process	GO:0006355	regulation of DNA-templated transcription	mafk	IDA		Zfish	PMID:24652768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern