Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAG
  • Mouse genes Mag
  • Rat genes Mag
  • Zfish genes mag
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mag

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	mag	IDA		Zfish	PMID:15229193
Molecular Function	GO:1905576	ganglioside GT1b binding	Mag	IMP		Mouse	MGI:MGI:5822923|PMID:27922006
Molecular Function	GO:1905576	ganglioside GT1b binding	Mag	IDA		Rat	PMID:8995428|RGD:12050139
Molecular Function	GO:0042802	identical protein binding	mag	IDA		Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	Mag	IPI	UniProtKB:P20917	Mouse	MGI:MGI:5822923|PMID:27922006
Molecular Function	GO:0005515	protein binding	Mag	IPI	PR:Q99PI8	Mouse	PMID:12839991
Molecular Function	GO:0005515	protein binding	Mag	IPI	RGD:3043	Rat	PMID:11733546|RGD:2304025
Molecular Function	GO:0005515	protein binding	Mag	IPI	UniProtKB:Q80WD1	Rat	PMID:15673660|RGD:12790657
Molecular Function	GO:0005515	protein binding	Mag	IPI	UniProtKB:Q99M75	Rat	PMID:15673660|RGD:12790657
Molecular Function	GO:0005515	protein binding	Mag	IPI	UniProtKB:Q80WD1	Rat	PMID:19420245|RGD:12050099
Molecular Function	GO:0005515	protein binding	Mag	IPI	UniProtKB:Q99M75	Rat	PMID:19420245|RGD:12050099
Molecular Function	GO:0005515	protein binding	mag	IPI	UniProtKB:A8BBF9	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	mag	IPI	UniProtKB:A8BBG3	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	mag	IPI	UniProtKB:A4JYF3	Zfish	PMID:18296487
Molecular Function	GO:0042803	protein homodimerization activity	Mag	IPI	UniProtKB:P20917	Mouse	MGI:MGI:5822923|PMID:27922006
Molecular Function	GO:0019901	protein kinase binding	Mag	IPI	RGD:2641	Rat	PMID:18381654|RGD:9685299
Molecular Function	GO:0033691	sialic acid binding	Mag	IDA		Mouse	MGI:MGI:5822923|PMID:27922006
Molecular Function	GO:0033691	sialic acid binding	Mag	IMP		Rat	PMID:19420245|RGD:12050099
Molecular Function	GO:0033691	sialic acid binding	Mag	IDA		Rat	PMID:8995428|RGD:12050139
Molecular Function	GO:0005102	signaling receptor binding	Mag	IPI	RGD:1307535	Rat	PMID:23132925|RGD:9685231
Cellular Component	GO:0043218	compact myelin	MAG	IDA		Human	PMID:6200494
Cellular Component	GO:0005737	cytoplasm	Mag	IDA		Rat	PMID:375239|RGD:9685298
Cellular Component	GO:0097453	mesaxon	Mag	IDA		Rat	PMID:12838505|RGD:1600847
Cellular Component	GO:0043209	myelin sheath	MAG	IDA		Human	PMID:6200494
Cellular Component	GO:0043209	myelin sheath	Mag	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043209	myelin sheath	Mag	IDA		Mouse	PMID:24101522
Cellular Component	GO:0043209	myelin sheath	Mag	IDA		Mouse	PMID:11283023
Cellular Component	GO:0035749	myelin sheath adaxonal region	Mag	IDA		Mouse	PMID:12718855
Cellular Component	GO:0035749	myelin sheath adaxonal region	Mag	IDA		Rat	PMID:375239|RGD:9685298
Cellular Component	GO:0033270	paranode region of axon	Mag	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Cellular Component	GO:0033270	paranode region of axon	Mag	IDA		Mouse	PMID:27583434
Cellular Component	GO:0005886	plasma membrane	MAG	IDA		Human	PMID:26179919
Cellular Component	GO:0005886	plasma membrane	Mag	IDA		Mouse	MGI:MGI:1202048|PMID:9482783
Cellular Component	GO:0005886	plasma membrane	Mag	IDA		Rat	PMID:1697293|RGD:9685229
Cellular Component	GO:0005886	plasma membrane	Mag	IMP		Rat	PMID:9298990|RGD:12050149
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Mag	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Mag	IDA		Rat	PMID:12838505|RGD:1600847
Biological Process	GO:0031103	axon regeneration	Mag	IGI	MGI:MGI:1328321	Mouse	PMID:20731761
Biological Process	GO:0007155	cell adhesion	Mag	IDA		Rat	PMID:8995428|RGD:12050139
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	Mag	IMP		Rat	PMID:9298990|RGD:12050149
Biological Process	GO:0071260	cellular response to mechanical stimulus	Mag	IEP		Rat	PMID:16140204|RGD:9685293
Biological Process	GO:0032289	central nervous system myelin formation	Mag	IGI	MGI:MGI:105980	Mouse	PMID:31641127
Biological Process	GO:0022010	central nervous system myelination	Mag	IMP		Mouse	MGI:MGI:1202048|PMID:9482783
Biological Process	GO:0042552	myelination	Mag	IGI	MGI:MGI:1914047	Mouse	PMID:31641127
Biological Process	GO:0042552	myelination	Mag	IMP	MGI:MGI:1857216	Mouse	PMID:31641127
Biological Process	GO:0042552	myelination	Mag	IGI	MGI:MGI:105980	Mouse	PMID:31641127
Biological Process	GO:0042552	myelination	Mag	IGI	MGI:MGI:1858201	Mouse	PMID:31641127
Biological Process	GO:0030517	negative regulation of axon extension	Mag	IMP		Rat	PMID:9298990|RGD:12050149
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Mag	IMP		Mouse	MGI:MGI:5819331|PMID:26335717
Biological Process	GO:0045665	negative regulation of neuron differentiation	Mag	IDA		Rat	PMID:19349915|RGD:9685287
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IMP		Mouse	MGI:MGI:5822923|PMID:27922006
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IMP		Mouse	MGI:MGI:3758400|PMID:17640868
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IDA		Rat	PMID:15282288|RGD:2314970
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IMP		Rat	PMID:17640868|RGD:12050140
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IMP		Rat	PMID:23132925|RGD:9685231
Biological Process	GO:0010977	negative regulation of neuron projection development	Mag	IMP		Rat	PMID:9298990|RGD:12050149
Biological Process	GO:0007399	nervous system development	Mag	IEP		Rat	PMID:2464408|RGD:9685425
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Mag	IDA		Rat	PMID:19349915|RGD:9685287
Biological Process	GO:0031643	positive regulation of myelination	Mag	IMP		Mouse	MGI:MGI:1352580|PMID:10625334
Biological Process	GO:0019226	transmission of nerve impulse	Mag	IMP	MGI:MGI:1857216	Mouse	PMID:20071523

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern