Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAGEL2
  • Mouse genes Magel2
  • Rat genes Magel2
  • Zfish genes ndnl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Magel2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:Q96QK1	Human	PMID:23452853
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:Q93009	Human	PMID:26365382
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:Q9UMX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:P63010	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	MAGEL2	IPI	UniProtKB:Q93009	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Magel2	IPI	UniProtKB:O54943|UniProtKB:Q9WTL8	Mouse	MGI:MGI:5607219|PMID:22208286
Molecular Function	GO:0005515	protein binding	Magel2	IPI	PR:Q9Z0W1	Mouse	PMID:14593116
Molecular Function	GO:0005515	protein binding	Magel2	IPI	PR:Q8K0X8	Mouse	PMID:15649943
Molecular Function	GO:0005515	protein binding	Magel2	IPI	PR:Q6TYB5	Mouse	PMID:15649943
Molecular Function	GO:0005515	protein binding	Magel2	IPI	PR:Q61501	Mouse	PMID:14593116
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MAGEL2	IMP		Human	PMID:23452853
Cellular Component	GO:0005737	cytoplasm	Magel2	IDA		Mouse	MGI:MGI:5607219|PMID:22208286
Cellular Component	GO:0005768	endosome	MAGEL2	IDA		Human	PMID:23452853
Cellular Component	GO:0005634	nucleus	Magel2	IDA		Mouse	MGI:MGI:5607219|PMID:22208286
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	MAGEL2	IDA		Human	PMID:23452853
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Magel2	IDA		Mouse	MGI:MGI:5607219|PMID:22208286
Biological Process	GO:0051127	positive regulation of actin nucleation	Magel2	IGI	MGI:MGI:1916017	Mouse	PMID:23452853
Biological Process	GO:0070534	protein K63-linked ubiquitination	MAGEL2	IMP		Human	PMID:23452853
Biological Process	GO:0042752	regulation of circadian rhythm	Magel2	IMP		Mouse	MGI:MGI:5607219|PMID:22208286
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	MAGEL2	IDA		Human	PMID:23452853

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern