Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAL
  • Mouse genes Mal
  • Rat genes Mal
  • Zfish genes mala.1,mala.2,malb,zgc:101772
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mal

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q93009	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q06187	Human	PMID:22366891
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P26715	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q16849-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q5T700	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8N539	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8N8F7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q92838	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BZL3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q5T700	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q92838	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:A0PJX4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O43278-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O43557	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O60894	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O95484	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:O95500	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P09693	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P22794	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P25942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P26715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P31431	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P31937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P35372-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P56880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:P78310	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q07108	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q09470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q13651	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q16322	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q16585	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q16671	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q495A1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q5T700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q6IBW4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q6UWW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q6UXG3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q6UXL0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q6UXU4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q7KYR7-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q86W47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q86YT9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8IVV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8N386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8N539	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8N6K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8WTT0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q8WUU8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q92838	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96CE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96CP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96DD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96FX8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96JQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q96LA5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q99946-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BQT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BVX2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BXK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BXU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9BZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9H0V9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9H7V2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9HBL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9NQX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9NV96-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9NWD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAL	IPI	UniProtKB:Q9Y4D2	Human	PMID:32296183
Molecular Function	GO:0019911	structural constituent of myelin sheath	MAL	IDA		Human	PMID:12153479
Molecular Function	GO:0019911	structural constituent of myelin sheath	Mal	IDA		Rat	PMID:12153479|RGD:625622
Cellular Component	GO:0016324	apical plasma membrane	Mal	IDA		Mouse	PMID:11032882
Cellular Component	GO:0005783	endoplasmic reticulum	MAL	IDA		Human	PMID:8132541
Cellular Component	GO:0120003	hinge region between urothelial plaques of apical plasma membrane	Mal	IMP	MGI:3053860	Mouse	PMID:22323295
Cellular Component	GO:0045121	membrane raft	MAL	IDA		Human	PMID:12153479
Cellular Component	GO:0045121	membrane raft	MAL	IDA		Human	PMID:23264465
Cellular Component	GO:0045121	membrane raft	Mal	IDA		Mouse	PMID:22323295
Cellular Component	GO:0045121	membrane raft	Mal	IDA		Rat	PMID:12153479|RGD:625622
Cellular Component	GO:0045121	membrane raft	Mal	IDA		Rat	PMID:9634556|RGD:1358759
Cellular Component	GO:0044853	plasma membrane raft	Mal	IMP	MGI:3053860	Mouse	PMID:15337780
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Mal	IDA		Rat	PMID:12153479|RGD:625622
Biological Process	GO:0022010	central nervous system myelination	Mal	IMP	MGI:3053860	Mouse	PMID:15337780
Biological Process	GO:0042552	myelination	Mal	IMP		Mouse	PMID:11032882
Biological Process	GO:0042552	myelination	Mal	IDA		Rat	PMID:7643216|RGD:729172
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Mal	IDA		Mouse	PMID:12776198
Biological Process	GO:0098737	protein insertion into plasma membrane	Mal	IMP	MGI:3053860	Mouse	PMID:22323295
Biological Process	GO:0002175	protein localization to paranode region of axon	Mal	IMP	MGI:3053860	Mouse	PMID:15337780

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern