Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MALRD1
  • Mouse genes Malrd1
  • Rat genes Malrd1
  • Zfish genes malrd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Malrd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Malrd1	IPI	PR:O35622	Mouse	PMID:23747249
Cellular Component	GO:0005737	cytoplasm	Malrd1	IDA		Mouse	PMID:23747249
Cellular Component	GO:0005794	Golgi apparatus	MALRD1	IDA		Human	GO_REF:0000052
Biological Process	GO:0042632	cholesterol homeostasis	Malrd1	IMP	MGI:MGI:2154956	Mouse	PMID:10744778
Biological Process	GO:0070858	negative regulation of bile acid biosynthetic process	Malrd1	IGI	MGI:MGI:1096383	Mouse	PMID:23747249
Biological Process	GO:0070858	negative regulation of bile acid biosynthetic process	Malrd1	IMP	MGI:MGI:2154956	Mouse	PMID:23747249

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern