Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAN1A1
  • Mouse genes Man1a
  • Rat genes Man1a1
  • Zfish genes man1a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Man1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1A1	IMP		Human	PMID:27108681
Cellular Component	GO:0031410	cytoplasmic vesicle	MAN1A1	IDA		Human	PMID:27108681
Cellular Component	GO:0005829	cytosol	MAN1A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	MAN1A1	IDA		Human	PMID:15308636
Cellular Component	GO:0070062	extracellular exosome	MAN1A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MAN1A1	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	MAN1A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000139	Golgi membrane	Man1a	IDA		Mouse	PMID:11042173
Cellular Component	GO:0016020	membrane	MAN1A1	HDA		Human	PMID:19946888
Biological Process	GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	MAN1A1	IDA		Human	PMID:27108681
Biological Process	GO:0045047	protein targeting to ER	MAN1A1	IMP		Human	PMID:27108681
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	MAN1A1	IDA		Human	PMID:27108681

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern