Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAN2A1
  • Mouse genes Man2a1
  • Rat genes Man2a1
  • Zfish genes man2a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Man2a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016787	hydrolase activity	Man2a1	IDA		Mouse	PMID:19710420
Molecular Function	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	Man2a1	IDA		Mouse	PMID:16754854
Molecular Function	GO:0042802	identical protein binding	Man2a1	IDA		Rat	PMID:1885615|RGD:38501079
Molecular Function	GO:0042802	identical protein binding	Man2a1	IDA		Rat	PMID:2246269|RGD:38501084
Molecular Function	GO:0015923	mannosidase activity	Man2a1	IDA		Mouse	PMID:16754854
Molecular Function	GO:0004572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	Man2a1	IDA		Rat	PMID:1885615|RGD:38501079
Molecular Function	GO:0042803	protein homodimerization activity	Man2a1	IDA		Rat	PMID:1885615|RGD:38501079
Molecular Function	GO:0042803	protein homodimerization activity	Man2a1	IDA		Rat	PMID:2246269|RGD:38501084
Cellular Component	GO:0005801	cis-Golgi network	Man2a1	IDA		Mouse	PMID:22841714
Cellular Component	GO:0070062	extracellular exosome	MAN2A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MAN2A1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	MAN2A1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Man2a1	IDA		Mouse	PMID:19710420
Cellular Component	GO:0005794	Golgi apparatus	Man2a1	IDA		Mouse	PMID:23000399
Cellular Component	GO:0005794	Golgi apparatus	Man2a1	IDA		Mouse	PMID:16204232
Cellular Component	GO:0005797	Golgi medial cisterna	MAN2A1	IDA		Human	PMID:21525244
Cellular Component	GO:0000139	Golgi membrane	Man2a1	IDA		Mouse	PMID:11042173
Cellular Component	GO:0000139	Golgi membrane	Man2a1	IDA		Rat	PMID:1885615|RGD:38501079
Cellular Component	GO:0000139	Golgi membrane	Man2a1	IDA		Rat	PMID:2246269|RGD:38501084
Cellular Component	GO:0016020	membrane	MAN2A1	HDA		Human	PMID:19946888
Biological Process	GO:0001701	in utero embryonic development	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0001889	liver development	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0048286	lung alveolus development	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0007005	mitochondrion organization	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0006491	N-glycan processing	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0006491	N-glycan processing	Man2a1	IDA		Rat	PMID:1885615|RGD:38501079
Biological Process	GO:0050769	positive regulation of neurogenesis	Man2a1	IMP	MGI:MGI:2159011	Mouse	PMID:20144606
Biological Process	GO:0050769	positive regulation of neurogenesis	Man2a1	IMP	MGI:MGI:2673381	Mouse	PMID:20144606
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Man2a1	IMP	MGI:MGI:2673381	Mouse	PMID:20144606
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Man2a1	IMP	MGI:MGI:2159011	Mouse	PMID:20144606
Biological Process	GO:0007033	vacuole organization	Man2a1	IGI	MGI:MGI:2150656	Mouse	PMID:16754854

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern