Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP1A
  • Mouse genes Map1a
  • Rat genes Map1a
  • Zfish genes map1aa,map1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Map1a	IDA		Mouse	MGI:MGI:5703671|PMID:26609151
Molecular Function	GO:0003779	actin binding	Map1a	IDA		Rat	PMID:11896150|RGD:71122
Molecular Function	GO:0005518	collagen binding	Map1a	IPI	RGD:619785	Rat	PMID:11418592|RGD:634622
Molecular Function	GO:0008093	cytoskeletal anchor activity	Map1a	IDA		Mouse	MGI:MGI:5703671|PMID:26609151
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Map1a	IPI	UniProtKB:P35436|UniProtKB:Q01097	Mouse	MGI:MGI:5703671|PMID:26609151
Molecular Function	GO:0008017	microtubule binding	Map1a	IDA		Mouse	PMID:17360631
Molecular Function	GO:0008017	microtubule binding	Map1a	IDA		Rat	PMID:9627185|RGD:13601988
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:Q9NRI5	Human	PMID:12812986
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:Q8NFB2	Human	PMID:15525354
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:O95990	Human	PMID:20543869
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:Q9H492	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:P31947	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	MAP1A	IPI	UniProtKB:Q9H492	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Map1a	IPI	UniProtKB:Q62108|UniProtKB:Q91XM9	Mouse	MGI:MGI:5703671|PMID:26609151
Molecular Function	GO:0005515	protein binding	Map1a	IPI	PR:Q62108	Mouse	PMID:11925566
Molecular Function	GO:0005515	protein binding	Map1a	IPI	PR:Q9ER97	Mouse	PMID:22079573
Molecular Function	GO:0005515	protein binding	Map1a	IPI	RGD:621869	Rat	PMID:15202935|RGD:2314804
Molecular Function	GO:0005515	protein binding	Map1a	IPI	UniProtKB:P31016	Rat	PMID:17220895|RGD:13432230
Molecular Function	GO:0005515	protein binding	Map1a	IPI	RGD:621315	Rat	PMID:7908909|RGD:633201
Molecular Function	GO:0005515	protein binding	Map1a	IPI	UniProtKB:P31016	Rat	PMID:9786987|RGD:8553274
Molecular Function	GO:0005515	protein binding	Map1a	IPI	UniProtKB:Q62696	Rat	PMID:9786987|RGD:8553274
Molecular Function	GO:0005515	protein binding	Map1a	IPI	UniProtKB:Q63622	Rat	PMID:9786987|RGD:8553274
Molecular Function	GO:0015631	tubulin binding	Map1a	IDA		Mouse	MGI:MGI:5703671|PMID:26609151
Cellular Component	GO:0030424	axon	Map1a	IDA		Rat	PMID:28426968|RGD:13514087
Cellular Component	GO:0030424	axon	Map1a	IDA		Rat	PMID:28521134|RGD:13441203
Cellular Component	GO:0030424	axon	Map1a	IDA		Rat	PMID:9627185|RGD:13601988
Cellular Component	GO:0043194	axon initial segment	Map1a	IDA		Mouse	MGI:MGI:5632407|PMID:25788676
Cellular Component	GO:0005737	cytoplasm	Map1a	IDA		Rat	PMID:2509111|RGD:13514077
Cellular Component	GO:0005829	cytosol	Map1a	IDA		Mouse	PMID:11925566
Cellular Component	GO:0030425	dendrite	Map1a	IDA		Mouse	MGI:MGI:5632407|PMID:25788676
Cellular Component	GO:0030425	dendrite	Map1a	IDA		Rat	PMID:28521134|RGD:13441203
Cellular Component	GO:0030425	dendrite	Map1a	IDA		Rat	PMID:9627185|RGD:13601988
Cellular Component	GO:0044307	dendritic branch	Map1a	IDA		Rat	PMID:2509111|RGD:13514077
Cellular Component	GO:1901588	dendritic microtubule	Map1a	IDA		Mouse	MGI:MGI:5632407|PMID:25788676
Cellular Component	GO:0043198	dendritic shaft	Map1a	IDA		Rat	PMID:2509111|RGD:13514077
Cellular Component	GO:0005875	microtubule associated complex	Map1a	IDA		Rat	PMID:11896150|RGD:71122
Cellular Component	GO:0005875	microtubule associated complex	Map1a	IDA		Rat	PMID:7908909|RGD:633201
Cellular Component	GO:0043005	neuron projection	Map1a	IDA		Rat	PMID:9627185|RGD:13601988
Cellular Component	GO:0043025	neuronal cell body	Map1a	IDA		Mouse	MGI:MGI:5632407|PMID:25788676
Cellular Component	GO:0043025	neuronal cell body	Map1a	IDA		Rat	PMID:9627185|RGD:13601988
Cellular Component	GO:0001750	photoreceptor outer segment	Map1a	IDA		Mouse	PMID:24664738
Cellular Component	GO:0014069	postsynaptic density	Map1a	IDA		Mouse	PMID:17114649
Cellular Component	GO:0150001	primary dendrite	Map1a	IDA		Rat	PMID:2509111|RGD:13514077
Biological Process	GO:0099641	anterograde axonal protein transport	Map1a	IGI	UniProtKB:Q91XM9	Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0008306	associative learning	Map1a	IMP		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0021782	glial cell development	map1ab	IMP	ZFIN:ZDB-CRISPR-191008-10,ZFIN:ZDB-CRISPR-191008-9	Zfish	PMID:30924555
Biological Process	GO:0007613	memory	Map1a	IMP		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0000226	microtubule cytoskeleton organization	Map1a	IMP		Mouse	MGI:MGI:5632407|PMID:25788676
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Map1a	IDA		Rat	PMID:11896150|RGD:71122
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Map1a	IDA		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:1902817	negative regulation of protein localization to microtubule	Map1a	IMP		Mouse	MGI:MGI:5632407|PMID:25788676
Biological Process	GO:0070050	neuron cellular homeostasis	Map1a	IMP		Mouse	MGI:MGI:5632407|PMID:25788676
Biological Process	GO:1990535	neuron projection maintenance	Map1a	IMP		Mouse	MGI:MGI:5632407|PMID:25788676
Biological Process	GO:0045494	photoreceptor cell maintenance	Map1a	IGI	MGI:MGI:109571	Mouse	PMID:22323461
Biological Process	GO:0045494	photoreceptor cell maintenance	Map1a	IGI	MGI:MGI:2651573	Mouse	PMID:22323461
Biological Process	GO:1903829	positive regulation of protein localization	Map1a	IMP		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	Map1a	IMP		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0048167	regulation of synaptic plasticity	Map1a	IMP		Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0060041	retina development in camera-type eye	map1ab	IMP	ZFIN:ZDB-CRISPR-191008-10,ZFIN:ZDB-CRISPR-191008-9	Zfish	PMID:30924555
Biological Process	GO:0099642	retrograde axonal protein transport	Map1a	IGI	UniProtKB:Q91XM9	Mouse	MGI:MGI:5703671|PMID:26609151
Biological Process	GO:0007605	sensory perception of sound	Map1a	IDA		Mouse	PMID:11925566
Biological Process	GO:0050882	voluntary musculoskeletal movement	Map1a	IMP		Mouse	MGI:MGI:5632407|PMID:25788676

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern