Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K11
  • Mouse genes Map3k11
  • Rat genes Map3k11
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Map3k11	IDA		Rat	PMID:11438570|RGD:2298689
Molecular Function	GO:0042802	identical protein binding	MAP3K11	IPI	UniProtKB:Q16584	Human	PMID:9829970
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	MAP3K11	IMP		Human	PMID:15258589
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	Map3k11	IDA		Rat	PMID:17064355|RGD:2298577
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K11	IMP		Human	PMID:15258589
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Map3k11	IDA		Rat	PMID:11438570|RGD:2298689
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Map3k11	IPI	RGD:1560043	Rat	PMID:14575811|RGD:2298566
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	MAP3K11	IPI	UniProtKB:Q12851	Human	PMID:17584736
Molecular Function	GO:0005515	protein binding	MAP3K11	IPI	UniProtKB:P35240	Human	PMID:20890305
Molecular Function	GO:0005515	protein binding	MAP3K11	IPI	UniProtKB:P60953	Human	PMID:20890305
Molecular Function	GO:0005515	protein binding	MAP3K11	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23857585
Molecular Function	GO:0005515	protein binding	MAP3K11	IPI	UniProtKB:P60953	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	MAP3K11	IPI	UniProtKB:P70218	Human	PMID:9003777
Molecular Function	GO:0005515	protein binding	Map3k11	IPI	PR:Q9ESN9	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Map3k11	IPI	RGD:70937	Rat	PMID:17348686|RGD:2298766
Molecular Function	GO:0005515	protein binding	Map3k11	IPI	UniProtKB:P42260	Rat	PMID:22483987|RGD:8554830
Molecular Function	GO:0042803	protein homodimerization activity	MAP3K11	IPI	UniProtKB:Q16584	Human	PMID:9829970
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAP3K11	IDA		Human	PMID:8195146
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Map3k11	IDA		Rat	PMID:17161586|RGD:2298583
Molecular Function	GO:0031267	small GTPase binding	Map3k11	IPI	RGD:71043	Rat	PMID:17161586|RGD:2298583
Cellular Component	GO:0005813	centrosome	MAP3K11	IDA		Human	PMID:12529434
Cellular Component	GO:0016020	membrane	MAP3K11	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	MAP3K11	IDA		Human	PMID:12529434
Biological Process	GO:0044843	cell cycle G1/S phase transition	MAP3K11	IMP		Human	PMID:15258589
Biological Process	GO:0008219	cell death	Map3k11	IMP		Rat	PMID:11416147|RGD:2302272
Biological Process	GO:0007254	JNK cascade	MAP3K11	IMP		Human	PMID:15258589
Biological Process	GO:0007254	JNK cascade	Map3k11	IDA		Rat	PMID:15680699|RGD:2298567
Biological Process	GO:0007254	JNK cascade	Map3k11	IDA		Rat	PMID:17064355|RGD:2298577
Biological Process	GO:0000165	MAPK cascade	MAP3K11	IMP		Human	PMID:15258589
Biological Process	GO:0007017	microtubule-based process	MAP3K11	IMP		Human	PMID:12529434
Biological Process	GO:0043065	positive regulation of apoptotic process	Map3k11	IMP		Rat	PMID:15069087|RGD:1359762
Biological Process	GO:0046330	positive regulation of JNK cascade	MAP3K11	IMP		Human	PMID:17584736
Biological Process	GO:0046330	positive regulation of JNK cascade	Map3k11	IDA		Rat	PMID:17064355|RGD:2298577
Biological Process	GO:0043507	positive regulation of JUN kinase activity	MAP3K11	IMP		Human	PMID:17584736
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Map3k11	IMP		Rat	PMID:11416147|RGD:2302272
Biological Process	GO:0046777	protein autophosphorylation	MAP3K11	IDA		Human	PMID:8195146
Biological Process	GO:0046777	protein autophosphorylation	Map3k11	IDA		Rat	PMID:17161586|RGD:2298583
Biological Process	GO:0006468	protein phosphorylation	MAP3K11	IDA		Human	PMID:11053428
Biological Process	GO:0006468	protein phosphorylation	Map3k11	IDA		Rat	PMID:11438570|RGD:2298689
Biological Process	GO:0006468	protein phosphorylation	Map3k11	IDA		Rat	PMID:17064355|RGD:2298577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern