Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K14
  • Mouse genes Map3k14
  • Rat genes Map3k14
  • Zfish genes arf2b,map3k14a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004704	NF-kappaB-inducing kinase activity	Map3k14	IDA		Mouse	MGI:MGI:1931349|PMID:11239468
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:10733566
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q60680-2	Human	PMID:10733566
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q14790	Human	PMID:12884866
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P07900	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P08238	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P36578	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62277	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62280	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62917	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q02878	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q16543	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q9Y6K9	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P05186	Human	PMID:15208311
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:16286467
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:16498412
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q60803	Human	PMID:17158868
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P59046	Human	PMID:17237370
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q13114	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P07900	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q13114	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q14974	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q16543	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P07900	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P36578	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62277	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62280	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P62917	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q02878	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q12933	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q13114	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q16543	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q9Y6K9	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q13114	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P07900	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q13114	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q9Y6K9	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:Q12933	Human	PMID:9020361
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O14920	Human	PMID:9520446
Molecular Function	GO:0005515	protein binding	MAP3K14	IPI	UniProtKB:O15111	Human	PMID:9520446
Molecular Function	GO:0005515	protein binding	Map3k14	IPI	UniProtKB:P48453|UniProtKB:P63328	Mouse	MGI:MGI:6216148|PMID:26029823
Molecular Function	GO:0005515	protein binding	Map3k14	IPI	UniProtKB:Q00653	Mouse	MGI:MGI:1931349|PMID:11239468
Molecular Function	GO:0004672	protein kinase activity	MAP3K14	IDA		Human	PMID:15001576
Molecular Function	GO:0004672	protein kinase activity	Map3k14	IMP		Rat	PMID:18722355|RGD:2313425
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAP3K14	EXP		Human	PMID:9520446
Cellular Component	GO:0005829	cytosol	MAP3K14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	MAP3K14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MAP3K14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MAP3K14	IDA		Human	GO_REF:0000052
Biological Process	GO:0071260	cellular response to mechanical stimulus	MAP3K14	IEP		Human	PMID:19593445
Biological Process	GO:0051607	defense response to virus	MAP3K14	IDA		Human	PMID:21478870
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Map3k14	IDA		Mouse	MGI:MGI:1931349|PMID:11239468
Biological Process	GO:0006955	immune response	Map3k14	IDA		Mouse	MGI:MGI:1931349|PMID:11239468
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	MAP3K14	IMP		Human	PMID:10094049
Biological Process	GO:0006468	protein phosphorylation	Map3k14	IMP		Rat	PMID:18722355|RGD:2313425

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern