Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K20
  • Mouse genes Map3k20
  • Rat genes Map3k20
  • Zfish genes map3k20a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k20

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MAP3K20	IDA		Human	PMID:11836244
Molecular Function	GO:0005524	ATP binding	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:11836244
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:12220515
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:14521931
Molecular Function	GO:0004706	JUN kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:32610081
Molecular Function	GO:0000287	magnesium ion binding	MAP3K20	IDA		Human	PMID:11836244
Molecular Function	GO:0000287	magnesium ion binding	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:11836244
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:15737997
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:32289254
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:32610081
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K20	IDA		Human	PMID:35857590
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Map3k20	IDA		Mouse	PMID:11042189
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:Q8N184	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:Q8N184	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:O75582	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:P63104	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAP3K20	IPI	UniProtKB:Q8N184	Human	PMID:31515488
Molecular Function	GO:0030295	protein kinase activator activity	MAP3K20	IDA		Human	PMID:32610081
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAP3K20	IDA		Human	PMID:35857590
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Molecular Function	GO:0043022	ribosome binding	MAP3K20	IDA		Human	PMID:32289254
Molecular Function	GO:0043022	ribosome binding	MAP3K20	IDA		Human	PMID:32610081
Molecular Function	GO:0003723	RNA binding	MAP3K20	HDA		Human	PMID:22681889
Molecular Function	GO:0070181	small ribosomal subunit rRNA binding	MAP3K20	IDA		Human	PMID:32289254
Cellular Component	GO:0005737	cytoplasm	Map3k20	IDA		Mouse	PMID:11042189
Cellular Component	GO:0005829	cytosol	MAP3K20	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Map3k20	IDA		Mouse	PMID:11042189
Biological Process	GO:0071480	cellular response to gamma radiation	MAP3K20	IDA		Human	PMID:11836244
Biological Process	GO:0071493	cellular response to UV-B	MAP3K20	IDA		Human	PMID:35857590
Biological Process	GO:0007010	cytoskeleton organization	Map3k20	IDA		Mouse	PMID:11042189
Biological Process	GO:0000077	DNA damage checkpoint signaling	MAP3K20	IMP		Human	PMID:11836244
Biological Process	GO:0042733	embryonic digit morphogenesis	MAP3K20	IMP		Human	PMID:26755636
Biological Process	GO:0140469	GCN2-mediated signaling	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0035556	intracellular signal transduction	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Biological Process	GO:0007254	JNK cascade	MAP3K20	IDA		Human	PMID:11836244
Biological Process	GO:0007254	JNK cascade	MAP3K20	IDA		Human	PMID:12220515
Biological Process	GO:0007254	JNK cascade	MAP3K20	IDA		Human	PMID:14521931
Biological Process	GO:0007254	JNK cascade	MAP3K20	IDA		Human	PMID:15737997
Biological Process	GO:0007254	JNK cascade	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0007254	JNK cascade	Map3k20	IMP		Mouse	MGI:MGI:5901799|PMID:27598200
Biological Process	GO:0060173	limb development	MAP3K20	IMP		Human	PMID:26755636
Biological Process	GO:0060173	limb development	Map3k20	IMP		Mouse	MGI:MGI:5771618|PMID:26755636
Biological Process	GO:0000165	MAPK cascade	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Biological Process	GO:0038066	p38MAPK cascade	MAP3K20	IDA		Human	PMID:11836244
Biological Process	GO:0038066	p38MAPK cascade	MAP3K20	IDA		Human	PMID:15737997
Biological Process	GO:0038066	p38MAPK cascade	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0038066	p38MAPK cascade	MAP3K20	IDA		Human	PMID:35857590
Biological Process	GO:0038066	p38MAPK cascade	Map3k20	IMP		Mouse	MGI:MGI:5901799|PMID:27598200
Biological Process	GO:0043065	positive regulation of apoptotic process	MAP3K20	IDA		Human	PMID:10924358
Biological Process	GO:1904291	positive regulation of mitotic DNA damage checkpoint	MAP3K20	IDA		Human	PMID:15342622
Biological Process	GO:0043068	positive regulation of programmed cell death	MAP3K20	IDA		Human	PMID:32289254
Biological Process	GO:0043068	positive regulation of programmed cell death	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0046777	protein autophosphorylation	MAP3K20	IDA		Human	PMID:12220515
Biological Process	GO:0046777	protein autophosphorylation	MAP3K20	IDA		Human	PMID:32289254
Biological Process	GO:0046777	protein autophosphorylation	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0006468	protein phosphorylation	MAP3K20	IDA		Human	PMID:11836244
Biological Process	GO:0006468	protein phosphorylation	Map3k20	IDA		Mouse	MGI:MGI:1930323|PMID:11042189
Biological Process	GO:0070269	pyroptosis	MAP3K20	IDA		Human	PMID:35857590
Biological Process	GO:0051403	stress-activated MAPK cascade	MAP3K20	IDA		Human	PMID:11836244
Biological Process	GO:0051403	stress-activated MAPK cascade	MAP3K20	IDA		Human	PMID:32289254
Biological Process	GO:0051403	stress-activated MAPK cascade	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0051403	stress-activated MAPK cascade	Map3k20	IMP		Mouse	MGI:MGI:6468889|PMID:32289254
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAP3K20	IDA		Human	PMID:15737997
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAP3K20	IDA		Human	PMID:18331592
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAP3K20	IDA		Human	PMID:20559024
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAP3K20	IDA		Human	PMID:32610081
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAP3K20	IDA		Human	PMID:35857590
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	Map3k20	IMP		Mouse	MGI:MGI:5901799|PMID:27598200

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern