Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K4
  • Mouse genes Map3k4
  • Rat genes Map3k4
  • Zfish genes map3k4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K4	IDA		Human	PMID:9305639
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K4	IDA		Human	PMID:9827804
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:O75293	Human	PMID:12052864
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:Q9BUZ4	Human	PMID:16157600
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:O75293	Human	PMID:16256071
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:P0CG48	Human	PMID:16256071
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:Q96B97	Human	PMID:16256071
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:O75369	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:P26651	Human	PMID:20221403
Molecular Function	GO:0005515	protein binding	MAP3K4	IPI	UniProtKB:Q96B97	Human	PMID:20221403
Molecular Function	GO:0005515	protein binding	Map3k4	IPI	UniProtKB:Q61382	Mouse	MGI:MGI:4821077|PMID:16157600
Molecular Function	GO:0005515	protein binding	Map3k4	IPI	PR:O35625	Mouse	PMID:12878610
Molecular Function	GO:0005515	protein binding	Map3k4	IPI	UniProtKB:Q14DJ8	Mouse	PMID:17681137
Molecular Function	GO:0004672	protein kinase activity	Map3k4	IDA		Mouse	MGI:MGI:4821077|PMID:16157600
Cellular Component	GO:0005737	cytoplasm	MAP3K4	IDA		Human	PMID:9827804
Cellular Component	GO:0005737	cytoplasm	Map3k4	IDA		Mouse	MGI:MGI:4821077|PMID:16157600
Biological Process	GO:0060718	chorionic trophoblast cell differentiation	Map3k4	IMP	MGI:MGI:3604209	Mouse	PMID:19289495
Biological Process	GO:0035556	intracellular signal transduction	Map3k4	IDA		Mouse	MGI:MGI:4821077|PMID:16157600
Biological Process	GO:0019100	male germ-line sex determination	Map3k4	IMP	MGI:MGI:1856634	Mouse	PMID:6855886
Biological Process	GO:0000165	MAPK cascade	MAP3K4	IDA		Human	PMID:9305639
Biological Process	GO:0000165	MAPK cascade	MAP3K4	IDA		Human	PMID:9827804
Biological Process	GO:0001890	placenta development	Map3k4	IMP	MGI:MGI:3604209	Mouse	PMID:19289495
Biological Process	GO:0043507	positive regulation of JUN kinase activity	MAP3K4	IDA		Human	PMID:9305639
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Map3k4	IDA		Mouse	MGI:MGI:4821077|PMID:16157600
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Map3k4	IMP		Mouse	PMID:12878610
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	MAP3K4	IDA		Human	PMID:9305639
Biological Process	GO:0051973	positive regulation of telomerase activity	MAP3K4	IMP		Human	PMID:21531765
Biological Process	GO:1904355	positive regulation of telomere capping	MAP3K4	IMP		Human	PMID:21531765
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	MAP3K4	IMP		Human	PMID:21531765
Biological Process	GO:0010468	regulation of gene expression	Map3k4	IMP	MGI:MGI:3604209	Mouse	PMID:19289495
Biological Process	GO:0010225	response to UV-C	MAP3K4	IMP		Human	PMID:9305639

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern