Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K8
  • Mouse genes Map3k8
  • Rat genes Map3k8
  • Zfish genes map3k8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Map3k8	EXP		Rat	PMID:8631303|RGD:11059568
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Map3k8	IDA		Rat	PMID:8631303|RGD:11059568
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:12832462
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q00653	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q8NFZ5	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q8NFZ5	Human	PMID:15169888
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q13526	Human	PMID:24265246
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q00653	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:Q8NFZ5	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	MAP3K8	IPI	UniProtKB:P19838	Human	PMID:35140242
Molecular Function	GO:0004672	protein kinase activity	Map3k8	IDA		Rat	PMID:8510223|RGD:151356926
Cellular Component	GO:0005829	cytosol	MAP3K8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Map3k8	IDA		Rat	PMID:9779826|RGD:70317
Biological Process	GO:0003231	cardiac ventricle development	Map3k8	IEP		Rat	PMID:9779826|RGD:70317
Biological Process	GO:1990349	gap junction-mediated intercellular transport	Map3k8	IMP		Rat	PMID:24249418|RGD:151356927

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern