Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP4
  • Mouse genes Map4
  • Rat genes Map4
  • Zfish genes map4l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	Map4	IDA		Mouse	PMID:21822276
Molecular Function	GO:0140778	microtubule stabilizing activity	MAP4	IDA		Human	PMID:34782749
Molecular Function	GO:0005515	protein binding	MAP4	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	MAP4	IPI	UniProtKB:Q9Y448	Human	PMID:29180244
Molecular Function	GO:0005515	protein binding	Map4	IPI	UniProtKB:Q149C2	Mouse	MGI:MGI:5707538|PMID:26487268
Molecular Function	GO:0003723	RNA binding	MAP4	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	MAP4	HDA		Human	PMID:22681889
Cellular Component	GO:0030424	axon	Map4	IDA		Rat	PMID:28426968|RGD:13514087
Cellular Component	GO:0005930	axoneme	MAP4	IDA		Human	PMID:23572511
Cellular Component	GO:0005874	microtubule	MAP4	IDA		Human	PMID:34782749
Cellular Component	GO:0005815	microtubule organizing center	MAP4	IDA		Human	PMID:29180244
Cellular Component	GO:0072686	mitotic spindle	MAP4	IDA		Human	PMID:21822276
Cellular Component	GO:0014069	postsynaptic density	Map4	IDA		Mouse	PMID:17114649
Biological Process	GO:0051301	cell division	MAP4	IMP		Human	PMID:21822276
Biological Process	GO:0061523	cilium disassembly	MAP4	IDA		Human	PMID:34782749
Biological Process	GO:0051294	establishment of spindle orientation	MAP4	IGI	UniProtKB:Q7Z460	Human	PMID:21822276
Biological Process	GO:0051294	establishment of spindle orientation	MAP4	IMP		Human	PMID:21822276
Biological Process	GO:0051294	establishment of spindle orientation	Map4	IDA		Mouse	PMID:21822276
Biological Process	GO:0000226	microtubule cytoskeleton organization	MAP4	IDA		Human	PMID:34782749
Biological Process	GO:0000226	microtubule cytoskeleton organization	Map4	IDA		Mouse	MGI:MGI:6154760|PMID:10542369
Biological Process	GO:0046785	microtubule polymerization	MAP4	IDA		Human	PMID:10791892
Biological Process	GO:0046785	microtubule polymerization	MAP4	IDA		Human	PMID:34782749
Biological Process	GO:0051012	microtubule sliding	MAP4	IMP		Human	PMID:21822276
Biological Process	GO:0051012	microtubule sliding	Map4	IDA		Mouse	PMID:21822276
Biological Process	GO:0007052	mitotic spindle organization	MAP4	IMP		Human	PMID:21822276
Biological Process	GO:0007052	mitotic spindle organization	Map4	IDA		Mouse	PMID:21822276
Biological Process	GO:1902856	negative regulation of non-motile cilium assembly	MAP4	IMP		Human	PMID:23572511

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern