Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mapkapk5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAPKAPK5
- Mouse genes Mapkapk5
- Rat genes Mapkapk5
- Zfish genes mapkapk5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapkapk5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Mapkapk5	IPI	UniProtKB:Q61532	Mouse	MGI:MGI:5306310\|PMID:15577943
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Mapkapk5	IPI	UniProtKB:Q6P5G0	Mouse	MGI:MGI:5306302\|PMID:16973613
Molecular Function	GO:0002039	p53 binding	MAPKAPK5	IDA		Human	PMID:17254968
Molecular Function	GO:0002039	p53 binding	Mapkapk5	IDA		Mouse	MGI:MGI:3697960\|PMID:17254968
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:P04637	Human	PMID:17254968
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:O43524	Human	PMID:21329882
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:P04792	Human	PMID:21575178
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q15109	Human	PMID:26758977
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	MAPKAPK5	IPI	UniProtKB:Q16659	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Mapkapk5	IPI	UniProtKB:Q921J2	Mouse	MGI:MGI:5306547\|PMID:21336308
Molecular Function	GO:0005515	protein binding	Mapkapk5	IPI	PR:A2CG49-8	Mouse	PMID:22508986
Molecular Function	GO:0005515	protein binding	Mapkapk5	IPI	PR:Q61532	Mouse	PMID:15538386
Molecular Function	GO:0005515	protein binding	Mapkapk5	IPI	PR:Q61532	Mouse	PMID:22508986
Molecular Function	GO:0004672	protein kinase activity	Mapkapk5	IDA		Mouse	PMID:22508986
Molecular Function	GO:0004672	protein kinase activity	Mapkapk5	IDA		Mouse	PMID:15538386
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPKAPK5	EXP		Human	PMID:17254968
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPKAPK5	IDA		Human	PMID:17254968
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPKAPK5	IDA		Human	PMID:21329882
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	MGI:MGI:3697960\|PMID:17254968
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	MGI:MGI:5306555\|PMID:20640477
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	MGI:MGI:5306302\|PMID:16973613
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	MGI:MGI:5306310\|PMID:15577943
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	MGI:MGI:5306547\|PMID:21336308
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapkapk5	IDA		Mouse	PMID:22508986
Cellular Component	GO:0005737	cytoplasm	Mapkapk5	IDA		Mouse	MGI:MGI:5306555\|PMID:20640477
Cellular Component	GO:0005737	cytoplasm	Mapkapk5	IDA		Mouse	MGI:MGI:5306310\|PMID:15577943
Cellular Component	GO:0005737	cytoplasm	Mapkapk5	IDA		Mouse	MGI:MGI:5306302\|PMID:16973613
Cellular Component	GO:0005737	cytoplasm	Mapkapk5	IDA		Mouse	PMID:15538386
Cellular Component	GO:0005829	cytosol	MAPKAPK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MAPKAPK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mapkapk5	IDA		Mouse	MGI:MGI:5306310\|PMID:15577943
Cellular Component	GO:0005634	nucleus	Mapkapk5	IDA		Mouse	MGI:MGI:5306555\|PMID:20640477
Cellular Component	GO:0005634	nucleus	Mapkapk5	IDA		Mouse	MGI:MGI:5306302\|PMID:16973613
Cellular Component	GO:0005634	nucleus	Mapkapk5	IDA		Mouse	PMID:15538386
Cellular Component	GO:0032991	protein-containing complex	Mapkapk5	IDA		Mouse	PMID:22508986
Cellular Component	GO:0032156	septin cytoskeleton	Mapkapk5	IDA		Mouse	PMID:22508986
Biological Process	GO:0032007	negative regulation of TOR signaling	Mapkapk5	IDA		Mouse	MGI:MGI:5306547\|PMID:21336308
Biological Process	GO:0060999	positive regulation of dendritic spine development	Mapkapk5	IMP	MGI:MGI:2680287	Mouse	PMID:22508986
Biological Process	GO:0060999	positive regulation of dendritic spine development	Mapkapk5	IGI	MGI:MGI:1354946	Mouse	PMID:22508986
Biological Process	GO:0051973	positive regulation of telomerase activity	MAPKAPK5	IMP		Human	PMID:21531765
Biological Process	GO:1904355	positive regulation of telomere capping	MAPKAPK5	IMP		Human	PMID:21531765
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	MAPKAPK5	IMP		Human	PMID:21531765
Biological Process	GO:0046777	protein autophosphorylation	MAPKAPK5	IDA		Human	PMID:21329882
Biological Process	GO:0007265	Ras protein signal transduction	MAPKAPK5	IDA		Human	PMID:17254968
Biological Process	GO:0007265	Ras protein signal transduction	Mapkapk5	IMP		Mouse	MGI:MGI:3697960\|PMID:17254968
Biological Process	GO:0006417	regulation of translation	MAPKAPK5	IDA		Human	PMID:21329882
Biological Process	GO:0090400	stress-induced premature senescence	MAPKAPK5	IDA		Human	PMID:17254968
Biological Process	GO:0090400	stress-induced premature senescence	Mapkapk5	IMP		Mouse	MGI:MGI:3697960\|PMID:17254968

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.