Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARCHF7
  • Mouse genes Marchf7
  • Rat genes Marchf7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marchf7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Marchf7	IPI	UniProtKB:P70398|UniProtKB:Q93009	Mouse	MGI:MGI:6162398|PMID:18410486
Molecular Function	GO:0097371	MDM2/MDM4 family protein binding	MARCHF7	IPI	UniProtKB:Q00987	Human	PMID:29295817
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:P61086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:Q15691	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:Q8IYI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF7	IPI	UniProtKB:Q9UPY8	Human	PMID:32296183
Molecular Function	GO:0043130	ubiquitin binding	Marchf7	IMP		Mouse	MGI:MGI:6162398|PMID:18410486
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	MARCHF7	IPI	UniProtKB:P61086	Human	PMID:18410486
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	MARCHF7	IPI	UniProtKB:P61088	Human	PMID:18410486
Cellular Component	GO:0005829	cytosol	Marchf7	IDA		Mouse	MGI:MGI:6162398|PMID:18410486
Cellular Component	GO:0005634	nucleus	MARCHF7	IDA		Human	PMID:29295817
Cellular Component	GO:0005634	nucleus	Marchf7	IDA		Mouse	MGI:MGI:6162398|PMID:18410486
Cellular Component	GO:0005886	plasma membrane	Marchf7	IDA		Mouse	MGI:MGI:6162398|PMID:18410486
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:1905524	negative regulation of protein autoubiquitination	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:0042130	negative regulation of T cell proliferation	Marchf7	IMP	MGI:MGI:3530008	Mouse	PMID:15670816
Biological Process	GO:0008284	positive regulation of cell population proliferation	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:1902916	positive regulation of protein polyubiquitination	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:0051865	protein autoubiquitination	Marchf7	IMP		Mouse	MGI:MGI:6162398|PMID:18410486
Biological Process	GO:0006513	protein monoubiquitination	MARCHF7	IDA		Human	PMID:24905733
Biological Process	GO:0050821	protein stabilization	MARCHF7	IMP		Human	PMID:29295817
Biological Process	GO:0002643	regulation of tolerance induction	Marchf7	IMP	MGI:MGI:3530008	Mouse	PMID:15670816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern