Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Marcks

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MARCKS
- Mouse genes Marcks
- Rat genes Marcks
- Zfish genes marcksa,marcksb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marcks

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Marcks	IPI	UniProtKB:P68135	Mouse	MGI:MGI:5882901\|PMID:15640140
Molecular Function	GO:0005516	calmodulin binding	Marcks	IPI	UniProtKB:P04464\|UniProtKB:P62157	Mouse	MGI:MGI:5882901\|PMID:15640140
Molecular Function	GO:0042802	identical protein binding	Marcks	IDA		Mouse	MGI:MGI:5882901\|PMID:15640140
Molecular Function	GO:0001786	phosphatidylserine binding	Marcks	IDA		Rat	PMID:8276751\|RGD:9685327
Molecular Function	GO:0005543	phospholipid binding	Marcks	IDA		Rat	PMID:8611023\|RGD:9685304
Molecular Function	GO:0005515	protein binding	marcksb	IPI	ZFIN:ZDB-GENE-110713-1	Zfish	PMID:31545789
Molecular Function	GO:0005080	protein kinase C binding	Marcks	IPI	UniProtKB:Q02111	Mouse	MGI:MGI:1326990\|PMID:9857183
Cellular Component	GO:0032432	actin filament bundle	Marcks	IDA		Mouse	MGI:MGI:5882901\|PMID:15640140
Cellular Component	GO:0043679	axon terminus	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0032059	bleb	Marcks	IDA		Rat	PMID:16341931\|RGD:9685306
Cellular Component	GO:0005938	cell cortex	Marcks	IDA		Mouse	PMID:15766745
Cellular Component	GO:0005813	centrosome	Marcks	IDA		Mouse	PMID:15766745
Cellular Component	GO:0033391	chromatoid body	Marcks	IDA		Rat	PMID:21764106\|RGD:9685331
Cellular Component	GO:0005737	cytoplasm	Marcks	IDA		Mouse	PMID:15766745
Cellular Component	GO:0005737	cytoplasm	Marcks	IDA		Rat	PMID:19683798\|RGD:8554397
Cellular Component	GO:0005829	cytosol	Marcks	IDA		Rat	PMID:16341931\|RGD:9685306
Cellular Component	GO:0044307	dendritic branch	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0043197	dendritic spine	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0070062	extracellular exosome	MARCKS	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MARCKS	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	MARCKS	HDA		Human	PMID:21423176
Cellular Component	GO:0042585	germinal vesicle	Marcks	IDA		Mouse	PMID:15766745
Cellular Component	GO:0098978	glutamatergic synapse	Marcks	IDA		Rat	PMID:16202710\|RGD:9685333
Cellular Component	GO:0098978	glutamatergic synapse	Marcks	IMP		Rat	PMID:16202710\|RGD:9685333
Cellular Component	GO:0030426	growth cone	Marcks	IDA		Rat	PMID:16987960\|RGD:2325857
Cellular Component	GO:0005764	lysosome	Marcks	IDA		Rat	PMID:11955957\|RGD:9685324
Cellular Component	GO:0016020	membrane	Marcks	IDA		Mouse	PMID:12888215
Cellular Component	GO:0016020	membrane	Marcks	IDA		Rat	PMID:16341931\|RGD:9685306
Cellular Component	GO:0005874	microtubule	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0043226	organelle	Marcks	IDA		Mouse	PMID:30655546
Cellular Component	GO:0001520	outer dense fiber	Marcks	IDA		Rat	PMID:21764106\|RGD:9685331
Cellular Component	GO:0005886	plasma membrane	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0099571	postsynaptic cytoskeleton	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0045211	postsynaptic membrane	Marcks	EXP		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0045211	postsynaptic membrane	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0099523	presynaptic cytosol	Marcks	EXP		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0099523	presynaptic cytosol	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0042734	presynaptic membrane	Marcks	EXP		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0042734	presynaptic membrane	Marcks	IDA		Rat	PMID:2332803\|RGD:9685308
Cellular Component	GO:0045202	synapse	Marcks	IDA		Rat	PMID:7676466\|RGD:9685336
Biological Process	GO:0051764	actin crosslink formation	Marcks	IDA		Mouse	MGI:MGI:5882901\|PMID:15640140
Biological Process	GO:0051017	actin filament bundle assembly	Marcks	IDA		Mouse	MGI:MGI:5882901\|PMID:15640140
Biological Process	GO:0007015	actin filament organization	Marcks	IMP		Rat	PMID:16987960\|RGD:2325857
Biological Process	GO:0031584	activation of phospholipase D activity	Marcks	IDA		Rat	PMID:16341931\|RGD:9685306
Biological Process	GO:0006915	apoptotic process	Marcks	IMP		Mouse	PMID:30655546
Biological Process	GO:0007420	brain development	Marcks	IEP		Rat	PMID:9674561\|RGD:9685307
Biological Process	GO:0007420	brain development	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:21809467
Biological Process	GO:0007420	brain development	marcksa	IMP	ZFIN:ZDB-MRPHLNO-131003-1	Zfish	PMID:21809467
Biological Process	GO:0051216	cartilage development	marcksb	IMP	ZFIN:ZDB-MRPHLNO-171107-8	Zfish	PMID:27554589
Biological Process	GO:0051216	cartilage development	marcksa	IMP	ZFIN:ZDB-MRPHLNO-171107-7	Zfish	PMID:27554589
Biological Process	GO:0031589	cell-substrate adhesion	Marcks	IDA		Rat	PMID:19509053\|RGD:9685335
Biological Process	GO:0007417	central nervous system development	marcksb	IMP	ZFIN:ZDB-MRPHLNO-171107-8	Zfish	PMID:27554589
Biological Process	GO:0007417	central nervous system development	marcksa	IMP	ZFIN:ZDB-MRPHLNO-171107-7	Zfish	PMID:27554589
Biological Process	GO:0060027	convergent extension involved in gastrulation	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:23537994
Biological Process	GO:0003381	epithelial cell morphogenesis involved in gastrulation	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:23537994
Biological Process	GO:0007369	gastrulation	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:23537994
Biological Process	GO:0006886	intracellular protein transport	Marcks	IMP		Rat	PMID:11882609\|RGD:633298
Biological Process	GO:0007005	mitochondrion organization	Marcks	IDA		Mouse	PMID:30655546
Biological Process	GO:0003407	neural retina development	marcksb	IMP	ZFIN:ZDB-MRPHLNO-171107-8	Zfish	PMID:27554589
Biological Process	GO:0003407	neural retina development	marcksa	IMP	ZFIN:ZDB-MRPHLNO-171107-7	Zfish	PMID:27554589
Biological Process	GO:0021915	neural tube development	Marcks	IMP		Mouse	PMID:30655546
Biological Process	GO:0022008	neurogenesis	Marcks	IMP		Mouse	PMID:30655546
Biological Process	GO:1900144	positive regulation of BMP secretion	marcksb	IGI	ZFIN:ZDB-GENE-110713-1	Zfish	PMID:31545789
Biological Process	GO:1900144	positive regulation of BMP secretion	marcksb	IMP	ZFIN:ZDB-GENO-200915-8	Zfish	PMID:31545789
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Marcks	IMP		Rat	PMID:16202710\|RGD:9685333
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	Marcks	IMP		Rat	PMID:19252893\|RGD:9685323
Biological Process	GO:0010976	positive regulation of neuron projection development	Marcks	IMP		Rat	PMID:16987960\|RGD:2325857
Biological Process	GO:1900020	positive regulation of protein kinase C activity	Marcks	IDA		Rat	PMID:16341931\|RGD:9685306
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Marcks	IDA		Rat	PMID:16202710\|RGD:9685333
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Marcks	IMP		Rat	PMID:16202710\|RGD:9685333
Biological Process	GO:0060541	respiratory system development	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:21809467
Biological Process	GO:0060541	respiratory system development	marcksa	IMP	ZFIN:ZDB-MRPHLNO-131003-1	Zfish	PMID:21809467
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Marcks	IDA		Mouse	PMID:30655546
Biological Process	GO:0010842	retina layer formation	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:21809467
Biological Process	GO:0010842	retina layer formation	marcksa	IMP	ZFIN:ZDB-MRPHLNO-131003-1	Zfish	PMID:21809467
Biological Process	GO:0035914	skeletal muscle cell differentiation	marcksb	IMP	ZFIN:ZDB-MRPHLNO-130809-8	Zfish	PMID:21809467
Biological Process	GO:0035914	skeletal muscle cell differentiation	marcksa	IMP	ZFIN:ZDB-MRPHLNO-131003-1	Zfish	PMID:21809467
Biological Process	GO:0003229	ventricular cardiac muscle tissue development	Marcks	IEP		Rat	PMID:9205551\|RGD:9685305

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.