Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARK1
  • Mouse genes Mark1
  • Rat genes Mark1
  • Zfish genes mark1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mark1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MARK1	IDA		Human	PMID:14976552
Molecular Function	GO:0005524	ATP binding	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Molecular Function	GO:0000287	magnesium ion binding	MARK1	IDA		Human	PMID:14976552
Molecular Function	GO:0000287	magnesium ion binding	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Molecular Function	GO:0070300	phosphatidic acid binding	MARK1	IDA		Human	PMID:21145462
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	MARK1	IDA		Human	PMID:21145462
Molecular Function	GO:0001786	phosphatidylserine binding	MARK1	IDA		Human	PMID:21145462
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:P10636	Human	PMID:23666762
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:O95988	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:P63172	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:Q8IY57-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARK1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0004672	protein kinase activity	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MARK1	IDA		Human	PMID:14976552
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mark1	IDA		Rat	PMID:14741102|RGD:8554024
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Molecular Function	GO:0050321	tau-protein kinase activity	MARK1	IMP		Human	PMID:23666762
Molecular Function	GO:0050321	tau-protein kinase activity	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Cellular Component	GO:0005737	cytoplasm	MARK1	IDA		Human	PMID:23666762
Cellular Component	GO:0005737	cytoplasm	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Cellular Component	GO:0005856	cytoskeleton	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Cellular Component	GO:0030425	dendrite	MARK1	IDA		Human	PMID:23666762
Cellular Component	GO:0005886	plasma membrane	MARK1	IDA		Human	PMID:21145462
Biological Process	GO:0007010	cytoskeleton organization	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Biological Process	GO:0051654	establishment of mitochondrion localization	Mark1	IMP		Mouse	MGI:MGI:3805160|PMID:18492799
Biological Process	GO:0035556	intracellular signal transduction	MARK1	IDA		Human	PMID:14976552
Biological Process	GO:0035556	intracellular signal transduction	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Biological Process	GO:0000226	microtubule cytoskeleton organization	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	MARK1	IDA		Human	PMID:31281935
Biological Process	GO:0010629	negative regulation of gene expression	MARK1	IDA		Human	PMID:31281935
Biological Process	GO:0001764	neuron migration	Mark1	IDA		Rat	PMID:14741102|RGD:8554024
Biological Process	GO:0010628	positive regulation of gene expression	MARK1	IDA		Human	PMID:31281935
Biological Process	GO:0006468	protein phosphorylation	MARK1	IDA		Human	PMID:14976552
Biological Process	GO:0006468	protein phosphorylation	MARK1	IMP	UniProtKB:Q96L34	Human	PMID:23666762
Biological Process	GO:0006468	protein phosphorylation	Mark1	IDA		Rat	PMID:9108484|RGD:633320
Biological Process	GO:0050773	regulation of dendrite development	Mark1	IMP		Mouse	MGI:MGI:3805160|PMID:18492799
Biological Process	GO:0010975	regulation of neuron projection development	Mark1	IMP		Mouse	MGI:MGI:3805160|PMID:18492799

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern