Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARS1
  • Mouse genes Mars1
  • Rat genes Mars1
  • Zfish genes mars1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mars1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004825	methionine-tRNA ligase activity	MARS1	IDA		Human	PMID:11714285
Molecular Function	GO:0004825	methionine-tRNA ligase activity	Mars1	IMP		Mouse	MGI:MGI:3055639|PMID:12060739
Molecular Function	GO:0005515	protein binding	Mars1	IPI	UniProtKB:A0A0G2K916,UniProtKB:B2GV38,UniProtKB:B5DFN4,UniProtKB:D4AA63,UniProtKB:F1M853,UniProtKB:P11250,UniProtKB:P51593,UniProtKB:P61107,UniProtKB:P62718,UniProtKB:P97612,UniProtKB:Q09167,UniProtKB:Q498M4,UniProtKB:Q5PPJ6,UniProtKB:Q5PPK9,UniProtKB:Q63569,UniProtKB:Q6AYJ7	Rat	PMID:27191843|RGD:11344934
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	MARS1	IDA		Human	PMID:10791971
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	MARS1	IDA		Human	PMID:19131329
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	Mars1	IDA		Mouse	MGI:MGI:3055639|PMID:12060739
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	Mars1	IDA		Rat	PMID:19524539|RGD:12793003
Cellular Component	GO:0005737	cytoplasm	MARS1	IDA		Human	PMID:10791971
Cellular Component	GO:0005737	cytoplasm	MARS1	IDA		Human	PMID:22424946
Cellular Component	GO:0005829	cytosol	MARS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	MARS1	IDA		Human	PMID:19289464
Cellular Component	GO:0070062	extracellular exosome	MARS1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	MARS1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Mars1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005730	nucleolus	MARS1	IDA		Human	PMID:10791971
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	MARS1	IDA		Human	PMID:10791971
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	MARS1	IDA		Human	PMID:10791971
Biological Process	GO:0006431	methionyl-tRNA aminoacylation	MARS1	IDA		Human	PMID:11714285
Biological Process	GO:0006431	methionyl-tRNA aminoacylation	MARS1	IMP		Human	PMID:33909043
Biological Process	GO:0006431	methionyl-tRNA aminoacylation	Mars1	IDA		Mouse	MGI:MGI:3055639|PMID:12060739
Biological Process	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	MARS1	IMP		Human	PMID:10791971
Biological Process	GO:0009303	rRNA transcription	MARS1	IMP		Human	PMID:10791971

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern