Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARVELD3
  • Mouse genes Marveld3
  • Rat genes Marveld3
  • Zfish genes marveld3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marveld3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	MARVELD3	IDA		Human	PMID:24567356
Molecular Function	GO:0005515	protein binding	MARVELD3	IPI	UniProtKB:Q8N4S9	Human	PMID:20164257
Cellular Component	GO:0005923	bicellular tight junction	MARVELD3	IDA		Human	PMID:20028514
Cellular Component	GO:0005923	bicellular tight junction	MARVELD3	IDA		Human	PMID:20164257
Cellular Component	GO:0005923	bicellular tight junction	Marveld3	IDA		Mouse	PMID:20164257
Cellular Component	GO:0031410	cytoplasmic vesicle	MARVELD3	IDA		Human	PMID:20164257
Biological Process	GO:0070830	bicellular tight junction assembly	MARVELD3	IMP		Human	PMID:20164257
Biological Process	GO:0045216	cell-cell junction organization	MARVELD3	IMP		Human	PMID:20164257
Biological Process	GO:0045216	cell-cell junction organization	Marveld3	IMP		Mouse	PMID:20164257
Biological Process	GO:0010633	negative regulation of epithelial cell migration	MARVELD3	IMP		Human	PMID:24567356
Biological Process	GO:0010633	negative regulation of epithelial cell migration	Marveld3	IDA		Mouse	PMID:24567356
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	MARVELD3	IMP		Human	PMID:24567356
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Marveld3	IDA		Mouse	PMID:24567356
Biological Process	GO:0046329	negative regulation of JNK cascade	MARVELD3	IMP		Human	PMID:24567356
Biological Process	GO:1902414	protein localization to cell junction	MARVELD3	IMP		Human	PMID:24567356
Biological Process	GO:0006970	response to osmotic stress	MARVELD3	IMP		Human	PMID:24567356

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern