Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MASP1
  • Mouse genes Masp1
  • Rat genes Masp1
  • Zfish genes masp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Masp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	MASP1	IDA		Human	PMID:18596036
Molecular Function	GO:0005509	calcium ion binding	Masp1	IDA		Rat	PMID:10913141|RGD:633275
Molecular Function	GO:0048306	calcium-dependent protein binding	MASP1	IPI	UniProtKB:P11226	Human	PMID:12421953
Molecular Function	GO:0048306	calcium-dependent protein binding	MASP1	IPI	UniProtKB:Q15485	Human	PMID:12421953
Molecular Function	GO:0048306	calcium-dependent protein binding	MASP1	IPI	UniProtKB:P11226	Human	PMID:18596036
Molecular Function	GO:0048306	calcium-dependent protein binding	Masp1	IPI	UniProtKB:P19999	Rat	PMID:10913141|RGD:633275
Molecular Function	GO:0008233	peptidase activity	MASP1	IDA		Human	PMID:10946292
Molecular Function	GO:0008233	peptidase activity	MASP1	IDA		Human	PMID:12538697
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:P05155	Human	PMID:10946292
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:O75636	Human	PMID:11907111
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:P11226	Human	PMID:20956340
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:Q9BWP8	Human	PMID:20956340
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:P11226	Human	PMID:22607836
Molecular Function	GO:0005515	protein binding	MASP1	IPI	UniProtKB:Q9BWP8	Human	PMID:24174618
Molecular Function	GO:0042803	protein homodimerization activity	MASP1	IPI	UniProtKB:P48740	Human	PMID:18596036
Molecular Function	GO:0042803	protein homodimerization activity	Masp1	IPI	UniProtKB:Q8CHN8	Rat	PMID:10913141|RGD:633275
Molecular Function	GO:0042803	protein homodimerization activity	Masp1	IPI	UniProtKB:Q8CHN8	Rat	PMID:15060079|RGD:1600552
Molecular Function	GO:0004252	serine-type endopeptidase activity	MASP1	IDA		Human	PMID:11527969
Molecular Function	GO:0004252	serine-type endopeptidase activity	Masp1	IDA		Mouse	MGI:MGI:3789229|PMID:18424734
Molecular Function	GO:0004252	serine-type endopeptidase activity	Masp1	IDA		Rat	PMID:15060079|RGD:1600552
Cellular Component	GO:0005737	cytoplasm	masp1	IDA		Zfish	PMID:25139857
Cellular Component	GO:0005829	cytosol	MASP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	MASP1	IDA		Human	PMID:11485744
Cellular Component	GO:0005615	extracellular space	Masp1	IDA		Mouse	MGI:MGI:3789229|PMID:18424734
Cellular Component	GO:0005615	extracellular space	Masp1	IDA		Rat	PMID:12847554|RGD:633273
Cellular Component	GO:0005654	nucleoplasm	MASP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0001867	complement activation, lectin pathway	MASP1	IMP		Human	PMID:17182967
Biological Process	GO:0001867	complement activation, lectin pathway	Masp1	IMP		Mouse	MGI:MGI:3789229|PMID:18424734
Biological Process	GO:1904888	cranial skeletal system development	masp1	IMP	ZFIN:ZDB-MRPHLNO-170720-2	Zfish	PMID:28258200
Biological Process	GO:0007507	heart development	masp1	IMP	ZFIN:ZDB-MRPHLNO-170720-2	Zfish	PMID:28258200
Biological Process	GO:0001755	neural crest cell migration	masp1	IGI	ZFIN:ZDB-MRPHLNO-110405-1,ZFIN:ZDB-MRPHLNO-110406-2,ZFIN:ZDB-MRPHLNO-110421-1,ZFIN:ZDB-MRPHLNO-110421-2	Zfish	PMID:21258343
Biological Process	GO:0001755	neural crest cell migration	masp1	IMP	ZFIN:ZDB-MRPHLNO-170720-2	Zfish	PMID:28258200
Biological Process	GO:0001755	neural crest cell migration	masp1	IMP	ZFIN:ZDB-MRPHLNO-110421-1,ZFIN:ZDB-MRPHLNO-110421-2	Zfish	PMID:21258343

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern