Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MBD1
  • Mouse genes Mbd1
  • Rat genes Mbd1
  • Zfish genes mbd1a,mbd1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mbd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Mbd1	IDA		Rat	PMID:18689796|RGD:9588634
Molecular Function	GO:0003677	DNA binding	Mbd1	IDA		Mouse	PMID:9774669
Molecular Function	GO:0010385	double-stranded methylated DNA binding	MBD1	IDA		Human	PMID:11371345
Molecular Function	GO:0008327	methyl-CpG binding	MBD1	IDA		Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q6VMQ6	Human	PMID:12665582
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:O43463	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:P45973	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q13547	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q92769	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:O15379	Human	PMID:16432238
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q15156	Human	PMID:16432238
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:P45973	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q8TBE0	Human	PMID:19666599
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:Q99435	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	MBD1	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	Mbd1	IPI	UniProtKB:Q9W6V6	Mouse	MGI:MGI:5447620|PMID:15777793
Molecular Function	GO:0045322	unmethylated CpG binding	MBD1	IDA		Human	PMID:29276034
Molecular Function	GO:0008270	zinc ion binding	MBD1	IDA		Human	PMID:29276034
Cellular Component	GO:0000785	chromatin	Mbd1	IDA		Mouse	PMID:9774669
Cellular Component	GO:0000785	chromatin	Mbd1	IDA		Rat	PMID:18689796|RGD:9588634
Cellular Component	GO:0005737	cytoplasm	Mbd1	IDA		Mouse	PMID:17546630
Cellular Component	GO:0005737	cytoplasm	Mbd1	IDA		Rat	PMID:19660178|RGD:9588289
Cellular Component	GO:0000792	heterochromatin	Mbd1	IDA		Mouse	PMID:14519686
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MBD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016363	nuclear matrix	Mbd1	IDA		Mouse	MGI:MGI:5447620|PMID:15777793
Cellular Component	GO:0016607	nuclear speck	Mbd1	IDA		Mouse	MGI:MGI:5447620|PMID:15777793
Cellular Component	GO:0005654	nucleoplasm	MBD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mbd1	IDA		Mouse	PMID:9774669
Cellular Component	GO:0005634	nucleus	Mbd1	IDA		Mouse	PMID:18604195
Cellular Component	GO:0005634	nucleus	Mbd1	IDA		Mouse	PMID:17546630
Cellular Component	GO:0005634	nucleus	Mbd1	IDA		Rat	PMID:19660178|RGD:9588289
Biological Process	GO:0007568	aging	Mbd1	IEP		Rat	PMID:16702315|RGD:9588248
Biological Process	GO:0007507	heart development	Mbd1	IEP		Rat	PMID:20735989|RGD:9588647
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	Mbd1	IDA		Rat	PMID:16881068|RGD:9588644
Biological Process	GO:0010629	negative regulation of gene expression	Mbd1	IDA		Rat	PMID:16881068|RGD:9588644
Biological Process	GO:0030182	neuron differentiation	Mbd1	IEP		Rat	PMID:19660178|RGD:9588289
Biological Process	GO:0044030	regulation of DNA methylation	Mbd1	IEP		Rat	PMID:20735989|RGD:9588647
Biological Process	GO:0042220	response to cocaine	Mbd1	IEP		Rat	PMID:16670375|RGD:2306447
Biological Process	GO:0032355	response to estradiol	Mbd1	IEP		Rat	PMID:22109888|RGD:9588666
Biological Process	GO:0031667	response to nutrient levels	Mbd1	IEP		Rat	PMID:16702315|RGD:9588248
Biological Process	GO:0014070	response to organic cyclic compound	Mbd1	IEP		Rat	PMID:22109888|RGD:9588666
Biological Process	GO:0009410	response to xenobiotic stimulus	Mbd1	IEP		Rat	PMID:16670375|RGD:2306447

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern