Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCHR1
  • Mouse genes Mchr1
  • Rat genes Mchr1
  • Zfish genes mchr1a,mchr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mchr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042562	hormone binding	Mchr1	IDA		Rat	PMID:12505154|RGD:628540
Molecular Function	GO:0030273	melanin-concentrating hormone receptor activity	Mchr1	IDA		Rat	PMID:12505154|RGD:628540
Molecular Function	GO:0005515	protein binding	Mchr1	IPI	RGD:621734	Rat	PMID:16945926|RGD:1624361
Molecular Function	GO:0005102	signaling receptor binding	Mchr1	IPI	PR:P30935	Mouse	PMID:23029470
Cellular Component	GO:0060170	ciliary membrane	Mchr1	IDA		Mouse	PMID:22139371
Cellular Component	GO:0005929	cilium	MCHR1	IDA		Human	PMID:28154160
Cellular Component	GO:0043005	neuron projection	Mchr1	IDA		Mouse	PMID:23029470
Cellular Component	GO:0043005	neuron projection	Mchr1	IDA		Mouse	PMID:23351594
Cellular Component	GO:0097730	non-motile cilium	Mchr1	IDA		Mouse	MGI:MGI:3778303|PMID:18334641
Cellular Component	GO:0097730	non-motile cilium	Mchr1	IDA		Mouse	PMID:23029470
Cellular Component	GO:0097730	non-motile cilium	Mchr1	IDA		Mouse	PMID:23351594
Cellular Component	GO:0005886	plasma membrane	Mchr1	IDA		Mouse	PMID:23029470
Cellular Component	GO:0005886	plasma membrane	Mchr1	IDA		Mouse	PMID:15950311
Cellular Component	GO:0005886	plasma membrane	Mchr1	IDA		Rat	PMID:15117878|RGD:1624362
Biological Process	GO:0007166	cell surface receptor signaling pathway	Mchr1	IMP		Rat	PMID:15117878|RGD:1624362
Biological Process	GO:0051928	positive regulation of calcium ion transport	Mchr1	IMP		Rat	PMID:15117878|RGD:1624362
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Mchr1	IMP		Rat	PMID:10559938|RGD:1624363

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern