Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCM9
  • Mouse genes Mcm9
  • Rat genes Mcm9,Mcmdc1
  • Zfish genes mcm9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcm9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	MCM9	IDA		Human	PMID:23401855
Molecular Function	GO:0003682	chromatin binding	MCM9	IDA		Human	PMID:26300262
Molecular Function	GO:0003682	chromatin binding	Mcm9	IDA		Mouse	MGI:MGI:5525985|PMID:23401855
Molecular Function	GO:0003678	DNA helicase activity	MCM9	IMP		Human	PMID:26300262
Molecular Function	GO:0019899	enzyme binding	MCM9	IPI	UniProtKB:Q9UJA3	Human	PMID:23401855
Molecular Function	GO:0019899	enzyme binding	MCM9	IPI	UniProtKB:Q9UJA3	Human	PMID:26300262
Molecular Function	GO:0032406	MutLbeta complex binding	MCM9	IDA		Human	PMID:26300262
Molecular Function	GO:0032407	MutSalpha complex binding	MCM9	IDA		Human	PMID:26300262
Molecular Function	GO:0032408	MutSbeta complex binding	MCM9	IDA		Human	PMID:26300262
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:Q06609	Human	PMID:23401855
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:Q9UJA3	Human	PMID:26215093
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:P20585|UniProtKB:P40692|UniProtKB:P43246|UniProtKB:P52701|UniProtKB:P54277	Human	PMID:26300262
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:P40692	Human	PMID:26300262
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:P52701	Human	PMID:26300262
Molecular Function	GO:0005515	protein binding	MCM9	IPI	UniProtKB:Q9UJA3	Human	PMID:26300262
Molecular Function	GO:0005515	protein binding	Mcm9	IPI	PR:P10126	Mouse	PMID:21689717
Molecular Function	GO:0044877	protein-containing complex binding	MCM9	IDA		Human	PMID:26215093
Cellular Component	GO:0097362	MCM8-MCM9 complex	MCM9	IPI		Human	PMID:26300262
Cellular Component	GO:0097362	MCM8-MCM9 complex	MCM9	IDA		Human	PMID:22771115
Cellular Component	GO:0097362	MCM8-MCM9 complex	MCM9	IDA		Human	PMID:23401855
Cellular Component	GO:0097362	MCM8-MCM9 complex	MCM9	IDA		Human	PMID:26215093
Cellular Component	GO:0097362	MCM8-MCM9 complex	MCM9	IDA		Human	PMID:26300262
Cellular Component	GO:0097362	MCM8-MCM9 complex	Mcm9	IDA		Mouse	MGI:MGI:5437561|PMID:22771120
Cellular Component	GO:0005634	nucleus	MCM9	IDA		Human	PMID:23401855
Cellular Component	GO:0005634	nucleus	MCM9	IDA		Human	PMID:26300262
Biological Process	GO:0006974	DNA damage response	MCM9	IDA		Human	PMID:22771115
Biological Process	GO:0006974	DNA damage response	Mcm9	IMP		Mouse	MGI:MGI:5437561|PMID:22771120
Biological Process	GO:0032508	DNA duplex unwinding	MCM9	IDA		Human	PMID:26300262
Biological Process	GO:0032508	DNA duplex unwinding	MCM9	IMP		Human	PMID:26300262
Biological Process	GO:0000724	double-strand break repair via homologous recombination	MCM9	IDA		Human	PMID:22771115
Biological Process	GO:0000724	double-strand break repair via homologous recombination	MCM9	IMP		Human	PMID:23401855
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Mcm9	IMP		Mouse	MGI:MGI:5437561|PMID:22771120
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Mcm9	IMP		Mouse	MGI:MGI:5525985|PMID:23401855
Biological Process	GO:0007292	female gamete generation	Mcm9	IMP		Mouse	MGI:MGI:5437561|PMID:22771120
Biological Process	GO:0007276	gamete generation	Mcm9	IMP		Mouse	MGI:MGI:5295089|PMID:21987787
Biological Process	GO:0070716	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	MCM9	IMP		Human	PMID:26300262
Biological Process	GO:0070716	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	Mcm9	IMP		Mouse	MGI:MGI:5705200|PMID:26300262
Biological Process	GO:0071168	protein localization to chromatin	MCM9	IMP		Human	PMID:23401855
Biological Process	GO:0071168	protein localization to chromatin	MCM9	IMP		Human	PMID:26300262
Biological Process	GO:0036298	recombinational interstrand cross-link repair	MCM9	IMP		Human	PMID:23401855
Biological Process	GO:0036298	recombinational interstrand cross-link repair	Mcm9	IMP		Mouse	MGI:MGI:5525985|PMID:23401855

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern