Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mecp2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MECP2
- Mouse genes Mecp2
- Rat genes Mecp2
- Zfish genes mecp2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mecp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Mecp2	IDA		Mouse	PMID:15608638
Molecular Function	GO:0003682	chromatin binding	Mecp2	IDA		Rat	PMID:23688924\|RGD:9589062
Molecular Function	GO:0031490	chromatin DNA binding	Mecp2	IDA		Rat	PMID:9038338\|RGD:1601325
Molecular Function	GO:0003677	DNA binding	Mecp2	IDA		Mouse	PMID:18511691
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:17108082
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mecp2	IDA		Mouse	PMID:18511691
Molecular Function	GO:0003700	DNA-binding transcription factor activity	mecp2	IDA		Zfish	PMID:26733807
Molecular Function	GO:0010385	double-stranded methylated DNA binding	MECP2	IMP		Human	PMID:17296936
Molecular Function	GO:0010385	double-stranded methylated DNA binding	Mecp2	IDA		Mouse	PMID:14593184
Molecular Function	GO:0010385	double-stranded methylated DNA binding	Mecp2	IDA		Mouse	PMID:15757975
Molecular Function	GO:0010385	double-stranded methylated DNA binding	Mecp2	IDA		Rat	PMID:16314321\|RGD:1601323
Molecular Function	GO:0010385	double-stranded methylated DNA binding	Mecp2	IDA		Rat	PMID:9038338\|RGD:1601325
Molecular Function	GO:0019899	enzyme binding	Mecp2	IPI	RGD:620979	Rat	PMID:12473678\|RGD:1359078
Molecular Function	GO:0000400	four-way junction DNA binding	Mecp2	IDA		Rat	PMID:16314321\|RGD:1601323
Molecular Function	GO:0042826	histone deacetylase binding	Mecp2	IPI	RGD:1309799	Rat	PMID:23671328\|RGD:9590112
Molecular Function	GO:0042826	histone deacetylase binding	Mecp2	IPI	RGD:619976	Rat	PMID:24441681\|RGD:9590255
Molecular Function	GO:0008327	methyl-CpG binding	Mecp2	IDA		Mouse	PMID:15342650
Molecular Function	GO:0008327	methyl-CpG binding	Mecp2	IDA		Mouse	PMID:17108082
Molecular Function	GO:0008327	methyl-CpG binding	Mecp2	IDA		Rat	PMID:12473678\|RGD:1359078
Molecular Function	GO:0060090	molecular adaptor activity	MECP2	EXP		Human	PMID:20405910
Molecular Function	GO:0140693	molecular condensate scaffold activity	MECP2	IMP		Human	PMID:32698189
Molecular Function	GO:0003729	mRNA binding	Mecp2	IDA		Mouse	PMID:15342650
Molecular Function	GO:0003676	nucleic acid binding	MECP2	EXP		Human	PMID:20405910
Molecular Function	GO:1990841	promoter-specific chromatin binding	Mecp2	IDA		Mouse	PMID:16782889
Molecular Function	GO:1990841	promoter-specific chromatin binding	Mecp2	IDA		Rat	PMID:21425435\|RGD:8552971
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P12755	Human	PMID:11441023
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q60974	Human	PMID:11441023
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P51531	Human	PMID:15696166
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9H2X6	Human	PMID:19820693
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9QZR5	Human	PMID:19820693
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q60974	Human	PMID:23770565
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q8BHJ5	Human	PMID:23770565
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q96ST3	Human	PMID:23770565
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9QXE7	Human	PMID:23770565
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9WU42	Human	PMID:23770565
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P61244	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O60907	Human	PMID:28348241
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9BZK7	Human	PMID:28348241
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O75398	Human	PMID:29636529
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O43196-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O75558	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P07948	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P10599	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P35222	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P57729	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:P63010-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q12824	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q16637-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q6DN90-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q6GQQ9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q6PCB6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q6PIV2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q7L576	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q7Z6I5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q86UV6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q86WT6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q8IUC2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q8TDB4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q8WUW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q8WWW0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q92993-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q96D59	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q96FW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q99457	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q99504	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9NS23-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9UHI6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9UII2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9ULX5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9Y2M5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MECP2	IPI	UniProtKB:Q9Y575-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q8BHJ5\|UniProtKB:Q9QXE7	Mouse	MGI:MGI:5904547\|PMID:28348241
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529\|PMID:20599664
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q3TKT4\|UniProtKB:Q60520	Mouse	MGI:MGI:6716953\|PMID:19602036
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:O70494	Mouse	MGI:MGI:6716954\|PMID:20385708
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q60987\|UniProtKB:Q60987	Mouse	MGI:MGI:5315776\|PMID:22357867
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:O35846	Mouse	MGI:MGI:3700432\|PMID:15696166
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q61687	Mouse	MGI:MGI:4439201\|PMID:20159591
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q9CU62\|UniProtKB:Q9CW03	Mouse	MGI:MGI:4439201\|PMID:20159591
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q9WU42	Mouse	MGI:MGI:5528617\|PMID:23770565
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q60520	Mouse	MGI:MGI:5528617\|PMID:23770565
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q3TKT4\|UniProtKB:Q61687	Mouse	MGI:MGI:6695677\|PMID:24270455
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:O88895	Mouse	MGI:MGI:5528617\|PMID:23770565
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:Q9Z1T5	Mouse	MGI:MGI:6163374\|PMID:29636529
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	PR:Q61687	Mouse	PMID:17296936
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	PR:Q01147	Mouse	PMID:18511691
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	UniProtKB:P46100	Rat	PMID:17296936\|RGD:10047280
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	RGD:1310555	Rat	PMID:21070191\|RGD:10045882
Molecular Function	GO:0005515	protein binding	Mecp2	IPI	RGD:2315525	Rat	PMID:21070191\|RGD:10045882
Molecular Function	GO:0019904	protein domain specific binding	Mecp2	IPI	RGD:1619064	Rat	PMID:24636259\|RGD:12789709
Molecular Function	GO:0003723	RNA binding	MECP2	HDA		Human	PMID:22658674
Molecular Function	GO:0035197	siRNA binding	Mecp2	IDA		Mouse	PMID:15342650
Molecular Function	GO:0003714	transcription corepressor activity	MECP2	IDA		Human	PMID:10773092
Molecular Function	GO:0003714	transcription corepressor activity	Mecp2	IDA		Mouse	MGI:MGI:5811980\|PMID:25722434
Molecular Function	GO:0008134	transcription factor binding	Mecp2	IPI	PR:Q60520	Mouse	PMID:14593184
Molecular Function	GO:0045322	unmethylated CpG binding	Mecp2	IDA		Rat	PMID:16314321\|RGD:1601323
Cellular Component	GO:0005813	centrosome	MECP2	IMP		Human	PMID:25527496
Cellular Component	GO:0000785	chromatin	Mecp2	IDA		Rat	PMID:9038338\|RGD:1601325
Cellular Component	GO:0005737	cytoplasm	Mecp2	IDA		Mouse	PMID:17546630
Cellular Component	GO:0005829	cytosol	Mecp2	IDA		Mouse	PMID:15939091
Cellular Component	GO:0005829	cytosol	Mecp2	IDA		Rat	PMID:17052801\|RGD:1601324
Cellular Component	GO:0005615	extracellular space	MECP2	HDA		Human	PMID:22664934
Cellular Component	GO:0098978	glutamatergic synapse	Mecp2	IDA		Rat	PMID:19442733\|RGD:11069248
Cellular Component	GO:0098978	glutamatergic synapse	Mecp2	IMP		Rat	PMID:19442733\|RGD:11069248
Cellular Component	GO:0000792	heterochromatin	MECP2	IDA		Human	PMID:11441023
Cellular Component	GO:0000792	heterochromatin	Mecp2	IDA		Mouse	PMID:17296936
Cellular Component	GO:0000792	heterochromatin	Mecp2	IDA		Mouse	PMID:14519686
Cellular Component	GO:0005654	nucleoplasm	MECP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MECP2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	MECP2	IDA		Human	PMID:11441023
Cellular Component	GO:0005634	nucleus	MECP2	IDA		Human	PMID:21782149
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:14593184
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:15939091
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:17997046
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:16199017
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:17546630
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:11809720
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Mouse	PMID:18511691
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Rat	PMID:11844796\|RGD:2289670
Cellular Component	GO:0005634	nucleus	Mecp2	IDA		Rat	PMID:17052801\|RGD:1601324
Cellular Component	GO:0032991	protein-containing complex	Mecp2	IDA		Rat	PMID:12473678\|RGD:1359078
Cellular Component	GO:0032991	protein-containing complex	Mecp2	IDA		Rat	PMID:21070191\|RGD:10045882
Biological Process	GO:0008344	adult locomotory behavior	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0008344	adult locomotory behavior	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:11242117
Biological Process	GO:0008306	associative learning	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:26158416
Biological Process	GO:0061564	axon development	mecp2	IMP	ZFIN:ZDB-MRPHLNO-171016-2	Zfish	PMID:28371371
Biological Process	GO:0061564	axon development	mecp2	IMP	ZFIN:ZDB-MRPHLNO-171016-1	Zfish	PMID:28371371
Biological Process	GO:0060385	axonogenesis involved in innervation	mecp2	IMP	ZFIN:ZDB-GENO-170418-3	Zfish	PMID:26733807
Biological Process	GO:0060385	axonogenesis involved in innervation	mecp2	IMP	ZFIN:ZDB-MRPHLNO-171204-1	Zfish	PMID:26733807
Biological Process	GO:0060385	axonogenesis involved in innervation	mecp2	IGI	ZFIN:ZDB-GENE-001019-1,ZFIN:ZDB-MRPHLNO-171204-1	Zfish	PMID:26733807
Biological Process	GO:0060385	axonogenesis involved in innervation	mecp2	IGI	ZFIN:ZDB-GENE-070912-187,ZFIN:ZDB-MRPHLNO-171204-1	Zfish	PMID:26733807
Biological Process	GO:0001662	behavioral fear response	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0001662	behavioral fear response	Mecp2	IMP	MGI:MGI:2158353,MGI:MGI:2176754	Mouse	PMID:16199017
Biological Process	GO:0006576	biogenic amine metabolic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15975715
Biological Process	GO:0007420	brain development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:18571096
Biological Process	GO:0032048	cardiolipin metabolic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17237885
Biological Process	GO:0050432	catecholamine secretion	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17050729
Biological Process	GO:0008283	cell population proliferation	Mecp2	IMP		Mouse	PMID:15939091
Biological Process	GO:0071317	cellular response to isoquinoline alkaloid	Mecp2	IDA		Rat	PMID:22262897\|RGD:12790719
Biological Process	GO:0035865	cellular response to potassium ion	Mecp2	IDA		Rat	PMID:14593183\|RGD:12790707
Biological Process	GO:0021549	cerebellum development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:18571096
Biological Process	GO:0021549	cerebellum development	Mecp2	IEP		Rat	PMID:14751287\|RGD:12743658
Biological Process	GO:0021987	cerebral cortex development	Mecp2	IEP		Rat	PMID:14751287\|RGD:12743658
Biological Process	GO:0007268	chemical synaptic transmission	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:16399702
Biological Process	GO:0016358	dendrite development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:17532643
Biological Process	GO:0016358	dendrite development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:15519245
Biological Process	GO:0009790	embryo development	Mecp2	IMP		Mouse	PMID:8563762
Biological Process	GO:0040029	epigenetic regulation of gene expression	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15757975
Biological Process	GO:0040029	epigenetic regulation of gene expression	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:17532643
Biological Process	GO:0060079	excitatory postsynaptic potential	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17920015
Biological Process	GO:0010467	gene expression	Mecp2	IDA		Mouse	PMID:30560934
Biological Process	GO:0010467	gene expression	Mecp2	IMP		Mouse	PMID:30560934
Biological Process	GO:0014009	glial cell proliferation	Mecp2	IMP		Mouse	PMID:15939091
Biological Process	GO:0008211	glucocorticoid metabolic process	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:17108082
Biological Process	GO:0006541	glutamine metabolic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17237885
Biological Process	GO:0007507	heart development	Mecp2	IEP		Rat	PMID:20735989\|RGD:9588647
Biological Process	GO:0031507	heterochromatin formation	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15608638
Biological Process	GO:0021766	hippocampus development	Mecp2	IEP		Rat	PMID:14751287\|RGD:12743658
Biological Process	GO:0016573	histone acetylation	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15757975
Biological Process	GO:0016571	histone methylation	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15757975
Biological Process	GO:0006954	inflammatory response	mecp2	IMP	ZFIN:ZDB-GENO-170418-3	Zfish	PMID:28993314
Biological Process	GO:0006020	inositol metabolic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17237885
Biological Process	GO:0007612	learning	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0007612	learning	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0007626	locomotory behavior	mecp2	IMP	ZFIN:ZDB-GENO-130826-1	Zfish	PMID:23874272
Biological Process	GO:0007616	long-term memory	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:16399702
Biological Process	GO:0060291	long-term synaptic potentiation	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:16087343
Biological Process	GO:0048286	lung alveolus development	Mecp2	IEP		Rat	PMID:21425435\|RGD:8552971
Biological Process	GO:0007613	memory	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:16399702
Biological Process	GO:0007052	mitotic spindle organization	MECP2	IMP		Human	PMID:25527496
Biological Process	GO:0033555	multicellular organismal response to stress	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:17108082
Biological Process	GO:0016525	negative regulation of angiogenesis	MECP2	IMP		Human	PMID:23960241
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	Mecp2	IDA		Rat	PMID:16881068\|RGD:9588644
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	MECP2	IDA		Human	PMID:23960241
Biological Process	GO:1903860	negative regulation of dendrite extension	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:0061000	negative regulation of dendritic spine development	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	MECP2	IDA		Human	PMID:11441023
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mecp2	IDA		Mouse	PMID:18511691
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:17108082
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mecp2	IDA		Rat	PMID:9038338\|RGD:1601325
Biological Process	GO:0010629	negative regulation of gene expression	MECP2	IDA		Human	PMID:23960241
Biological Process	GO:0010629	negative regulation of gene expression	Mecp2	IMP		Rat	PMID:19217433\|RGD:11069822
Biological Process	GO:0090327	negative regulation of locomotion involved in locomotory behavior	Mecp2	IMP		Rat	PMID:27313794\|RGD:11568037
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17997046
Biological Process	GO:2000635	negative regulation of primary miRNA processing	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:0032091	negative regulation of protein binding	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:1903941	negative regulation of respiratory gaseous exchange	Mecp2	IMP		Rat	PMID:27313794\|RGD:11568037
Biological Process	GO:0051151	negative regulation of smooth muscle cell differentiation	Mecp2	IMP		Mouse	MGI:MGI:5811980\|PMID:25722434
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15608638
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mecp2	IDA		Mouse	PMID:10888872
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mecp2	IDA		Rat	PMID:9038338\|RGD:1601325
Biological Process	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	Mecp2	IDA		Mouse	MGI:MGI:5811980\|PMID:25722434
Biological Process	GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17544925
Biological Process	GO:0007528	neuromuscular junction development	mecp2	IMP	ZFIN:ZDB-MRPHLNO-171016-1	Zfish	PMID:28371371
Biological Process	GO:0007528	neuromuscular junction development	mecp2	IMP	ZFIN:ZDB-MRPHLNO-171016-2	Zfish	PMID:28371371
Biological Process	GO:0050905	neuromuscular process	Mecp2	IMP	MGI:MGI:2158353,MGI:MGI:2176754	Mouse	PMID:16199017
Biological Process	GO:0050905	neuromuscular process	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0050884	neuromuscular process controlling posture	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:11242117
Biological Process	GO:0030182	neuron differentiation	Mecp2	IMP		Mouse	PMID:30560934
Biological Process	GO:0030182	neuron differentiation	Mecp2	IDA		Mouse	PMID:30560934
Biological Process	GO:0030182	neuron differentiation	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:15345242
Biological Process	GO:0030182	neuron differentiation	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0042551	neuron maturation	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:18295506
Biological Process	GO:0042551	neuron maturation	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:15519245
Biological Process	GO:0042551	neuron maturation	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:17532643
Biological Process	GO:0031175	neuron projection development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:15345242
Biological Process	GO:0007219	Notch signaling pathway	Mecp2	IDA		Mouse	PMID:30560934
Biological Process	GO:0021772	olfactory bulb development	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0014003	oligodendrocyte development	Mecp2	IEP		Rat	PMID:26140854\|RGD:11343660
Biological Process	GO:0048709	oligodendrocyte differentiation	Mecp2	IEP		Rat	PMID:20697302\|RGD:12789708
Biological Process	GO:0046470	phosphatidylcholine metabolic process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17237885
Biological Process	GO:1901953	positive regulation of anterograde dense core granule transport	Mecp2	IMP		Rat	PMID:22127389\|RGD:12790715
Biological Process	GO:1905492	positive regulation of branching morphogenesis of a nerve	Mecp2	IMP		Rat	PMID:19442733\|RGD:11069248
Biological Process	GO:0008284	positive regulation of cell population proliferation	MECP2	IMP		Human	PMID:25527496
Biological Process	GO:1903861	positive regulation of dendrite extension	Mecp2	IMP		Rat	PMID:19442733\|RGD:11069248
Biological Process	GO:0060999	positive regulation of dendritic spine development	Mecp2	IMP		Rat	PMID:24188180\|RGD:12789443
Biological Process	GO:1905643	positive regulation of DNA methylation	MECP2	IDA		Human	PMID:23960241
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mecp2	IDA		Mouse	PMID:18511691
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	MECP2	IMP		Human	PMID:25527496
Biological Process	GO:0010628	positive regulation of gene expression	Mecp2	IMP		Rat	PMID:24636259\|RGD:12789709
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Mecp2	IMP		Mouse	PMID:15939091
Biological Process	GO:1900114	positive regulation of histone H3-K9 trimethylation	Mecp2	IDA		Mouse	MGI:MGI:5811980\|PMID:25722434
Biological Process	GO:0090063	positive regulation of microtubule nucleation	MECP2	IMP		Human	PMID:25527496
Biological Process	GO:1901956	positive regulation of retrograde dense core granule transport	Mecp2	IMP		Rat	PMID:22127389\|RGD:12790715
Biological Process	GO:0031915	positive regulation of synaptic plasticity	Mecp2	IMP		Rat	PMID:23015442\|RGD:12790708
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17050729
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:16782889
Biological Process	GO:0009791	post-embryonic development	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0099054	presynapse assembly	mecp2	IGI	ZFIN:ZDB-MRPHLNO-100205-1,ZFIN:ZDB-MRPHLNO-171016-1	Zfish	PMID:28371371
Biological Process	GO:0021740	principal sensory nucleus of trigeminal nerve development	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0019230	proprioception	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0019230	proprioception	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0008104	protein localization	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17296936
Biological Process	GO:0099611	regulation of action potential firing threshold	Mecp2	IMP		Rat	PMID:27313794\|RGD:11568037
Biological Process	GO:0044030	regulation of DNA methylation	Mecp2	IEP		Rat	PMID:20735989\|RGD:9588647
Biological Process	GO:0044030	regulation of DNA methylation	Mecp2	IMP		Rat	PMID:20735989\|RGD:9588647
Biological Process	GO:0010468	regulation of gene expression	Mecp2	IDA		Mouse	PMID:18203756
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	MECP2	IMP		Human	PMID:15608638
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15608638
Biological Process	GO:0051570	regulation of histone H3-K9 methylation	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:15608638
Biological Process	GO:0045664	regulation of neuron differentiation	mecp2	IGI	ZFIN:ZDB-MRPHLNO-150925-1,ZFIN:ZDB-MRPHLNO-150925-2	Zfish	PMID:25948585
Biological Process	GO:0045664	regulation of neuron differentiation	mecp2	IMP	ZFIN:ZDB-MRPHLNO-150925-1	Zfish	PMID:25948585
Biological Process	GO:0045664	regulation of neuron differentiation	mecp2	IMP	ZFIN:ZDB-CRISPR-150925-4	Zfish	PMID:25948585
Biological Process	GO:0045664	regulation of neuron differentiation	mecp2	IGI	ZFIN:ZDB-MRPHLNO-150130-1,ZFIN:ZDB-MRPHLNO-150925-1	Zfish	PMID:25948585
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:16354910
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0050807	regulation of synapse organization	Mecp2	IDA		Rat	PMID:19442733\|RGD:11069248
Biological Process	GO:0050807	regulation of synapse organization	Mecp2	IMP		Rat	PMID:19442733\|RGD:11069248
Biological Process	GO:0048167	regulation of synaptic plasticity	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:16399702
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Mecp2	IMP	MGI:MGI:3800596	Mouse	PMID:16467389
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:11242117
Biological Process	GO:0042220	response to cocaine	Mecp2	IEP		Rat	PMID:20711185\|RGD:12789445
Biological Process	GO:0042220	response to cocaine	Mecp2	IDA		Rat	PMID:23688924\|RGD:9589062
Biological Process	GO:0032355	response to estradiol	Mecp2	IEP		Rat	PMID:22109888\|RGD:9588666
Biological Process	GO:0001666	response to hypoxia	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17997046
Biological Process	GO:0010212	response to ionizing radiation	Mecp2	IEP		Rat	PMID:17148264\|RGD:1601086
Biological Process	GO:0010288	response to lead ion	Mecp2	IEP		Rat	PMID:23246732\|RGD:9588316
Biological Process	GO:0014070	response to organic cyclic compound	Mecp2	IEP		Rat	PMID:22109888\|RGD:9588666
Biological Process	GO:0051707	response to other organism	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17997046
Biological Process	GO:0019233	sensory perception of pain	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0050975	sensory perception of touch	mecp2	IGI	ZFIN:ZDB-GENE-001019-1,ZFIN:ZDB-MRPHLNO-171204-1	Zfish	PMID:26733807
Biological Process	GO:0050975	sensory perception of touch	mecp2	IGI	ZFIN:ZDB-GENE-070912-187,ZFIN:ZDB-MRPHLNO-171204-1	Zfish	PMID:26733807
Biological Process	GO:0035176	social behavior	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0035176	social behavior	Mecp2	IMP	MGI:MGI:2158353,MGI:MGI:2176754	Mouse	PMID:16199017
Biological Process	GO:0035176	social behavior	Mecp2	IMP		Rat	PMID:18614683\|RGD:12789706
Biological Process	GO:0035176	social behavior	Mecp2	IMP		Rat	PMID:27313794\|RGD:11568037
Biological Process	GO:0021510	spinal cord development	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0001964	startle response	Mecp2	IMP	MGI:MGI:2137555	Mouse	PMID:18321864
Biological Process	GO:0021756	striatum development	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0007416	synapse assembly	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:18295506
Biological Process	GO:0007416	synapse assembly	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17920015
Biological Process	GO:0021794	thalamus development	Mecp2	IEP		Rat	PMID:12605461\|RGD:12790706
Biological Process	GO:0099191	trans-synaptic signaling by BDNF	Mecp2	IMP	MGI:MGI:2137311	Mouse	PMID:17050729
Biological Process	GO:0021591	ventricular system development	Mecp2	IMP	MGI:MGI:2158354	Mouse	PMID:18571096
Biological Process	GO:0008542	visual learning	Mecp2	IMP	MGI:MGI:2183727	Mouse	PMID:16399702

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.