Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED16
  • Mouse genes Med16
  • Rat genes Med16
  • Zfish genes med16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	MED16	IDA		Human	PMID:10198638
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:O60244	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:O75448	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:Q71SY5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:Q9ULK4	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:Q9ULK4	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED16	IPI	UniProtKB:Q71SY5	Human	PMID:25792360
Molecular Function	GO:0003713	transcription coactivator activity	MED16	IDA		Human	PMID:10198638
Molecular Function	GO:0003713	transcription coactivator activity	MED16	IDA		Human	PMID:12218053
Cellular Component	GO:0070847	core mediator complex	MED16	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	MED16	IDA		Human	PMID:10198638
Cellular Component	GO:0016592	mediator complex	Med16	IDA		Mouse	PMID:12093747
Cellular Component	GO:0016592	mediator complex	Med16	IDA		Mouse	PMID:15340084
Cellular Component	GO:0016020	membrane	MED16	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	MED16	IDA		Human	PMID:24882805
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MED16	IDA		Human	PMID:10198638
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	MED16	IDA		Human	PMID:12218053

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern