Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BORCS8-MEF2B,MEF2B
  • Mouse genes Mef2b
  • Rat genes Mef2b
  • Zfish genes mef2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mef2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MEF2B	IDA		Human	PMID:7760790
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2b	IDA		Mouse	MGI:MGI:81047|PMID:8668199
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2b	IMP		Mouse	MGI:MGI:81047|PMID:8668199
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mef2b	IDA		Mouse	PMID:12130539
Molecular Function	GO:0042826	histone deacetylase binding	MEF2B	IPI	UniProtKB:Q9UKV0	Human	PMID:15567413
Molecular Function	GO:0042826	histone deacetylase binding	Mef2b	IDA		Mouse	PMID:17158926
Molecular Function	GO:0005515	protein binding	MEF2B	IPI	UniProtKB:Q9Y6J0	Human	PMID:12700764
Molecular Function	GO:0005515	protein binding	MEF2B	IPI	UniProtKB:Q9Y6J0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MEF2B	IPI	UniProtKB:P56524-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MEF2B	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MEF2B	IDA		Human	PMID:7760790
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mef2b	IDA		Mouse	MGI:MGI:81047|PMID:8668199
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MEF2B	IDA		Human	PMID:28473536
Cellular Component	GO:0030054	cell junction	MEF2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	MEF2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MEF2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005667	transcription regulator complex	MEF2B	IDA		Human	PMID:15567413
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2B	IDA		Human	PMID:7760790
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2b	IMP		Mouse	MGI:MGI:81047|PMID:8668199
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2b	IDA		Mouse	PMID:9443808
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mef2b	IDA		Mouse	PMID:12130539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern