Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEF2C
  • Mouse genes Mef2c
  • Rat genes Mef2c
  • Zfish genes mef2ca,mef2cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mef2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Mef2c	IDA		Mouse	PMID:18086704
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	PMID:16140986
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	PMID:20399744
Molecular Function	GO:0003677	DNA binding	Mef2c	IDA		Mouse	PMID:14762206
Molecular Function	GO:0003677	DNA binding	Mef2c	IDA		Rat	PMID:11782488|RGD:2298794
Molecular Function	GO:0003677	DNA binding	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MEF2C	IDA		Human	PMID:15486975
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	MGI:MGI:5572908|PMID:7760790
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	MGI:MGI:81047|PMID:8668199
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	PMID:17875930
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	PMID:8506376
Molecular Function	GO:0003700	DNA-binding transcription factor activity	MEF2C	IDA		Human	PMID:16043483
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mef2c	IDA		Mouse	PMID:12130539
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	MEF2C	IDA		Human	PMID:8455629
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	MGI:MGI:5049797|PMID:21610032
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	PMID:18093911
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mef2c	IDA		Mouse	PMID:17420000
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MEF2C	IPI	UniProtKB:Q15796	Human	PMID:11160896
Molecular Function	GO:0042826	histone deacetylase binding	Mef2c	IPI	UniProtKB:P56524	Mouse	MGI:MGI:4359371|PMID:10983972
Molecular Function	GO:0071837	HMG box domain binding	Mef2c	IPI	UniProtKB:P43680	Mouse	MGI:MGI:5142376|PMID:11554755
Molecular Function	GO:0071837	HMG box domain binding	Mef2c	IPI	UniProtKB:Q04888	Mouse	MGI:MGI:5049797|PMID:21610032
Molecular Function	GO:0003680	minor groove of adenine-thymine-rich DNA binding	MEF2C	IDA		Human	PMID:15486975
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:P61296	Human	PMID:15486975
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q92585	Human	PMID:16510869
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q13163	Human	PMID:18588859
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q9UKV0	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q9UQL6	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q9UKV0	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:B2RWS6	Human	PMID:21556048
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q8VCR8	Human	PMID:21556048
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q9H1R3	Human	PMID:21556048
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q9UQL6	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:Q05086	Human	PMID:31988313
Molecular Function	GO:0005515	protein binding	MEF2C	IPI	UniProtKB:P56524-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q0ZCJ7|UniProtKB:Q8VIM5	Mouse	MGI:MGI:3653312|PMID:16818234
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q91V92	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q9WVS8	Mouse	MGI:MGI:5284808|PMID:14515274
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q91ZP3-2	Mouse	MGI:MGI:4441113|PMID:19753306
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q8WUI4|UniProtKB:Q9QZR5	Mouse	MGI:MGI:5494340|PMID:23565059
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q8VCR8	Mouse	MGI:MGI:3829850|PMID:18955699
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	PR:Q61026	Mouse	PMID:12130539
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	RGD:621207	Rat	PMID:15485823|RGD:5132893
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:P61295	Rat	PMID:15486975|RGD:8554739
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:A1L1K8	Rat	PMID:15862299|RGD:8553316
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:Q5JVS0	Rat	PMID:15862299|RGD:8553316
Molecular Function	GO:0005515	protein binding	Mef2c	IPI	UniProtKB:P0C865	Rat	PMID:19103177|RGD:8554846
Molecular Function	GO:0046982	protein heterodimerization activity	MEF2C	IPI	UniProtKB:Q63943	Human	PMID:9858528
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:5572908|PMID:7760790
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:81047|PMID:8668199
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:4440396|PMID:20181743
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	PMID:19477969
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MEF2C	IDA		Human	PMID:8455629
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:3578591|PMID:15890826
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MEF2C	IPI	UniProtKB:O96004	Human	PMID:16043483
Molecular Function	GO:0043565	sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:5013486|PMID:21556048
Molecular Function	GO:0043565	sequence-specific DNA binding	Mef2c	IDA		Mouse	MGI:MGI:5049797|PMID:21610032
Molecular Function	GO:0043565	sequence-specific DNA binding	Mef2c	IDA		Mouse	PMID:17336904
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MEF2C	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Mef2c	IDA		Mouse	MGI:MGI:4940010|PMID:8035824
Molecular Function	GO:0000976	transcription cis-regulatory region binding	mef2ca	IDA		Zfish	PMID:8951797
Cellular Component	GO:0005737	cytoplasm	MEF2C	IDA		Human	PMID:8455629
Cellular Component	GO:0005737	cytoplasm	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Cellular Component	GO:0005829	cytosol	Mef2c	IDA		Rat	PMID:19103177|RGD:8554846
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MEF2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	MEF2C	IDA		Human	PMID:18079734
Cellular Component	GO:0005654	nucleoplasm	MEF2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MEF2C	IDA		Human	PMID:16510869
Cellular Component	GO:0005634	nucleus	MEF2C	IDA		Human	PMID:21170291
Cellular Component	GO:0005634	nucleus	MEF2C	IDA		Human	PMID:24008018
Cellular Component	GO:0005634	nucleus	MEF2C	IDA		Human	PMID:8455629
Cellular Component	GO:0005634	nucleus	MEF2C	IDA		Human	PMID:9770491
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	MGI:MGI:5284792|PMID:15998798
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	MGI:MGI:5142376|PMID:11554755
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	MGI:MGI:4440396|PMID:20181743
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	MGI:MGI:5049797|PMID:21610032
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	PMID:11081517
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Mouse	PMID:18086704
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Rat	PMID:15862299|RGD:8553316
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Rat	PMID:17696759|RGD:8553739
Cellular Component	GO:0005634	nucleus	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Cellular Component	GO:0032991	protein-containing complex	MEF2C	IDA		Human	PMID:15486975
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	mef2ca	IDA		Zfish	PMID:28586646
Cellular Component	GO:0030017	sarcomere	Mef2c	IDA		Rat	PMID:15862299|RGD:8553316
Biological Process	GO:0001782	B cell homeostasis	Mef2c	IMP		Mouse	MGI:MGI:3844189|PMID:19211936
Biological Process	GO:0042100	B cell proliferation	Mef2c	IMP		Mouse	MGI:MGI:3795835|PMID:18438409
Biological Process	GO:0050853	B cell receptor signaling pathway	Mef2c	IMP		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:0001568	blood vessel development	Mef2c	IMP		Mouse	PMID:17336904
Biological Process	GO:0001568	blood vessel development	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:9778514
Biological Process	GO:0001974	blood vessel remodeling	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:9162005
Biological Process	GO:0001974	blood vessel remodeling	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:10395786
Biological Process	GO:0060349	bone morphogenesis	mef2ca	IMP	ZFIN:ZDB-GENO-071023-1	Zfish	PMID:12588850
Biological Process	GO:0060349	bone morphogenesis	mef2ca	IMP	ZFIN:ZDB-GENO-140217-9	Zfish	PMID:24269905
Biological Process	GO:0060349	bone morphogenesis	mef2ca	IMP	ZFIN:ZDB-GENO-980202-931	Zfish	PMID:12588850
Biological Process	GO:0055013	cardiac muscle cell development	mef2cb	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0055013	cardiac muscle cell development	mef2ca	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0055007	cardiac muscle cell differentiation	Mef2c	IGI	MGI:MGI:102541	Mouse	PMID:20691899
Biological Process	GO:0055007	cardiac muscle cell differentiation	Mef2c	IGI	MGI:MGI:95664	Mouse	PMID:20691899
Biological Process	GO:0055007	cardiac muscle cell differentiation	Mef2c	IGI	MGI:MGI:97350	Mouse	PMID:19035347
Biological Process	GO:0055007	cardiac muscle cell differentiation	mef2cb	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0055007	cardiac muscle cell differentiation	mef2cb	IGI	ZFIN:ZDB-GENO-980202-931,ZFIN:ZDB-MRPHLNO-121031-1	Zfish	PMID:22750409
Biological Process	GO:0055007	cardiac muscle cell differentiation	mef2ca	IGI	ZFIN:ZDB-GENO-980202-931,ZFIN:ZDB-MRPHLNO-121031-1	Zfish	PMID:22750409
Biological Process	GO:0055007	cardiac muscle cell differentiation	mef2ca	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0055007	cardiac muscle cell differentiation	mef2ca	IMP	ZFIN:ZDB-GENO-071023-2	Zfish	PMID:22750409
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	Mef2c	IMP		Mouse	PMID:10531040
Biological Process	GO:0003211	cardiac ventricle formation	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0003211	cardiac ventricle formation	Mef2c	IGI	MGI:MGI:97350	Mouse	PMID:19035347
Biological Process	GO:0060536	cartilage morphogenesis	Mef2c	IMP	MGI:MGI:3603182	Mouse	PMID:17420000
Biological Process	GO:0060536	cartilage morphogenesis	mef2ca	IMP	ZFIN:ZDB-GENO-980202-931	Zfish	PMID:9007254
Biological Process	GO:0045165	cell fate commitment	Mef2c	IMP	MGI:MGI:3603182	Mouse	PMID:19169261
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0071838	cell proliferation in bone marrow	Mef2c	IGI	MGI:MGI:2684360	Mouse	PMID:18278031
Biological Process	GO:0071277	cellular response to calcium ion	Mef2c	IDA		Mouse	MGI:MGI:5284792|PMID:15998798
Biological Process	GO:0071498	cellular response to fluid shear stress	Mef2c	IDA		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0071333	cellular response to glucose stimulus	Mef2c	IEP		Rat	PMID:18413674|RGD:2312263
Biological Process	GO:0071363	cellular response to growth factor stimulus	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Mef2c	IDA		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:0071407	cellular response to organic cyclic compound	Mef2c	IEP		Rat	PMID:11073966|RGD:5132895
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	MEF2C	IDA		Human	PMID:17696759
Biological Process	GO:0071300	cellular response to retinoic acid	Mef2c	IDA		Rat	PMID:17568621|RGD:5131615
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	MEF2C	IDA		Human	PMID:9770491
Biological Process	GO:0035984	cellular response to trichostatin A	Mef2c	IDA		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Mef2c	IDA		Mouse	MGI:MGI:5284785|PMID:16775627
Biological Process	GO:0002062	chondrocyte differentiation	Mef2c	IGI	MGI:MGI:99533	Mouse	PMID:17336904
Biological Process	GO:0021542	dentate gyrus development	Mef2c	IEP		Rat	PMID:18949272|RGD:5131610
Biological Process	GO:0006351	DNA-templated transcription	mef2cb	IDA		Zfish	PMID:24844180
Biological Process	GO:0006351	DNA-templated transcription	mef2ca	IDA		Zfish	PMID:24844180
Biological Process	GO:0035050	embryonic heart tube development	Mef2c	IMP	MGI:MGI:2687362	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Mef2c	IGI	MGI:MGI:105923	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Mef2c	IMP	MGI:MGI:2158947	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Mef2c	IGI	MGI:MGI:2179061	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Mef2c	IMP	MGI:MGI:1857637	Mouse	PMID:30735130
Biological Process	GO:0003143	embryonic heart tube morphogenesis	mef2cb	IMP	ZFIN:ZDB-MRPHLNO-110523-1	Zfish	PMID:21466801
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Mef2c	IMP	MGI:MGI:3603182	Mouse	PMID:17420000
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	Mef2c	IMP	MGI:MGI:3603182	Mouse	PMID:17420000
Biological Process	GO:0001958	endochondral ossification	Mef2c	IGI	MGI:MGI:99533	Mouse	PMID:17336904
Biological Process	GO:0001958	endochondral ossification	Mef2c	IMP		Mouse	PMID:17336904
Biological Process	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0060079	excitatory postsynaptic potential	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0060079	excitatory postsynaptic potential	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0010467	gene expression	Mef2c	IMP	MGI:MGI:3718323	Mouse	PMID:30735130
Biological Process	GO:0002467	germinal center formation	Mef2c	IMP		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:0072102	glomerulus morphogenesis	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0007507	heart development	MEF2C	IEP		Human	PMID:10458488
Biological Process	GO:0007507	heart development	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:9778514
Biological Process	GO:0007507	heart development	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:10395786
Biological Process	GO:0007507	heart development	Mef2c	IEP		Rat	PMID:15486975|RGD:8554739
Biological Process	GO:0007507	heart development	mef2cb	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0007507	heart development	mef2cb	IMP	ZFIN:ZDB-MRPHLNO-121031-1	Zfish	PMID:22750409
Biological Process	GO:0007507	heart development	mef2ca	IGI	ZFIN:ZDB-MRPHLNO-060328-2,ZFIN:ZDB-MRPHLNO-091230-1	Zfish	PMID:19204083
Biological Process	GO:0007507	heart development	mef2ca	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2cb	IGI	ZFIN:ZDB-GENO-980202-931,ZFIN:ZDB-MRPHLNO-121031-1	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2cb	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2ca	IMP	ZFIN:ZDB-GENO-071023-2	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2ca	IGI	ZFIN:ZDB-GENO-121116-9	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2ca	IGI	ZFIN:ZDB-MRPHLNO-070730-5	Zfish	PMID:22750409
Biological Process	GO:0060914	heart formation	mef2ca	IGI	ZFIN:ZDB-GENO-980202-931,ZFIN:ZDB-MRPHLNO-121031-1	Zfish	PMID:22750409
Biological Process	GO:0001947	heart looping	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0006959	humoral immune response	Mef2c	IMP		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:0007611	learning or memory	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0007611	learning or memory	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0036076	ligamentous ossification	mef2ca	IMP		Zfish	PMID:27789622
Biological Process	GO:0000165	MAPK cascade	MEF2C	IMP		Human	PMID:11160896
Biological Process	GO:0000165	MAPK cascade	MEF2C	IDA		Human	PMID:9858528
Biological Process	GO:0000165	MAPK cascade	Mef2c	IMP		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:0000165	MAPK cascade	Mef2c	IDA		Mouse	MGI:MGI:5284808|PMID:14515274
Biological Process	GO:0030318	melanocyte differentiation	Mef2c	IMP		Mouse	MGI:MGI:5049797|PMID:21610032
Biological Process	GO:0030224	monocyte differentiation	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:18326819
Biological Process	GO:0007521	muscle cell fate determination	Mef2c	IMP	MGI:MGI:3718323	Mouse	PMID:17786239
Biological Process	GO:0014902	myotube differentiation	MEF2C	IEP		Human	PMID:8455629
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	MEF2C	IGI	RNAcentral:URS000001C659_9606,RNAcentral:URS000075BB59_9606	Human	PMID:26184978
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0010629	negative regulation of gene expression	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Mef2c	IDA		Mouse	MGI:MGI:5284763|PMID:18579729
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Mef2c	IDA		Rat	PMID:19103177|RGD:8554846
Biological Process	GO:0030279	negative regulation of ossification	MEF2C	IDA		Human	PMID:17696759
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MEF2C	IMP		Human	PMID:18079734
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:98834	Mouse	PMID:7677753
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	MEF2C	IGI	RNAcentral:URS000001C659_9606,RNAcentral:URS000075BB59_9606	Human	PMID:26184978
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	MEF2C	IDA		Human	PMID:28799067
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	MEF2C	IGI	RNAcentral:URS000001C659_9606,RNAcentral:URS000075BB59_9606	Human	PMID:26184978
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	MEF2C	IDA		Human	PMID:28799067
Biological Process	GO:1905563	negative regulation of vascular endothelial cell proliferation	MEF2C	IGI	RNAcentral:URS000001C659_9606,RNAcentral:URS000075BB59_9606	Human	PMID:26184978
Biological Process	GO:0072160	nephron tubule epithelial cell differentiation	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0014033	neural crest cell differentiation	Mef2c	IMP		Mouse	MGI:MGI:5049797|PMID:21610032
Biological Process	GO:0048666	neuron development	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0030182	neuron differentiation	MEF2C	IEP		Human	PMID:8455629
Biological Process	GO:0030182	neuron differentiation	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0001764	neuron migration	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0001649	osteoblast differentiation	Mef2c	IEP		Mouse	MGI:MGI:5285459|PMID:21652706
Biological Process	GO:0001649	osteoblast differentiation	Mef2c	IGI	MGI:MGI:99533	Mouse	PMID:17336904
Biological Process	GO:0003151	outflow tract morphogenesis	Mef2c	IGI	MGI:MGI:97350	Mouse	PMID:19035347
Biological Process	GO:0030220	platelet formation	Mef2c	IMP		Mouse	MGI:MGI:3844189|PMID:19211936
Biological Process	GO:0010694	positive regulation of alkaline phosphatase activity	Mef2c	IMP		Mouse	MGI:MGI:5285459|PMID:21652706
Biological Process	GO:0030890	positive regulation of B cell proliferation	Mef2c	IMP		Mouse	MGI:MGI:3829850|PMID:18955699
Biological Process	GO:2000987	positive regulation of behavioral fear response	Mef2c	IMP		Mouse	MGI:MGI:5284763|PMID:18579729
Biological Process	GO:0030501	positive regulation of bone mineralization	Mef2c	IMP		Mouse	MGI:MGI:5285459|PMID:21652706
Biological Process	GO:2000727	positive regulation of cardiac muscle cell differentiation	MEF2C	IDA		Human	PMID:9857019
Biological Process	GO:2000727	positive regulation of cardiac muscle cell differentiation	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Mef2c	IMP		Rat	PMID:19654000|RGD:5131609
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	Mef2c	IGI	MGI:MGI:2684360	Mouse	PMID:18278031
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MEF2C	IDA		Human	PMID:17696759
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IDA		Mouse	MGI:MGI:5284808|PMID:14515274
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IDA		Mouse	MGI:MGI:5142376|PMID:11554755
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IDA		Mouse	MGI:MGI:5049797|PMID:21610032
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IDA		Mouse	PMID:9738004
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:9162005
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IMP		Rat	PMID:17696759|RGD:8553739
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mef2c	IDA		Rat	PMID:19654000|RGD:5131609
Biological Process	GO:0010628	positive regulation of gene expression	MEF2C	IDA		Human	PMID:21556048
Biological Process	GO:0010628	positive regulation of gene expression	MEF2C	IDA		Human	PMID:9857019
Biological Process	GO:0010628	positive regulation of gene expression	Mef2c	IMP		Mouse	MGI:MGI:5285459|PMID:21652706
Biological Process	GO:0010628	positive regulation of gene expression	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0010628	positive regulation of gene expression	Mef2c	IDA		Mouse	MGI:MGI:5284763|PMID:18579729
Biological Process	GO:2000111	positive regulation of macrophage apoptotic process	Mef2c	IMP		Mouse	MGI:MGI:5284785|PMID:16775627
Biological Process	GO:0043406	positive regulation of MAP kinase activity	Mef2c	IDA		Rat	PMID:19103177|RGD:8554846
Biological Process	GO:0045663	positive regulation of myoblast differentiation	MEF2C	IMP		Human	PMID:9770491
Biological Process	GO:0045666	positive regulation of neuron differentiation	Mef2c	IDA		Mouse	MGI:MGI:5284763|PMID:18579729
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Mef2c	IMP		Mouse	MGI:MGI:5285459|PMID:21652706
Biological Process	GO:2001016	positive regulation of skeletal muscle cell differentiation	MEF2C	IDA		Human	PMID:21556048
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	MEF2C	IMP		Human	PMID:9770491
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2C	IMP		Human	PMID:11160896
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2C	IDA		Human	PMID:15486975
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2C	IDA		Human	PMID:16043483
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2C	IMP		Human	PMID:21556048
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MEF2C	IDA		Human	PMID:8455629
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	MGI:MGI:5572908|PMID:7760790
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IMP		Mouse	MGI:MGI:3578591|PMID:15890826
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	MGI:MGI:81047|PMID:8668199
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:98510	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:97275	Mouse	PMID:15743821
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	UniProtKB:P20695	Mouse	PMID:15743821
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:99533	Mouse	PMID:18093911
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	PMID:17352741
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	PMID:17336904
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:96919	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:3036234	Mouse	PMID:17336904
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:101926	Mouse	PMID:17420000
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	UniProtKB:P56524	Mouse	PMID:15743821
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	PMID:18086704
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IDA		Mouse	PMID:16818234
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IGI	MGI:MGI:97276	Mouse	PMID:20399744
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mef2c	IMP		Rat	PMID:19654000|RGD:5131609
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	mef2ca	IDA		Zfish	PMID:8951797
Biological Process	GO:0003138	primary heart field specification	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:2000311	regulation of AMPA receptor activity	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0060998	regulation of dendritic spine development	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0006355	regulation of DNA-templated transcription	MEF2C	IDA		Human	PMID:24008018
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mef2c	IDA		Mouse	PMID:12130539
Biological Process	GO:0002634	regulation of germinal center formation	Mef2c	IMP		Mouse	MGI:MGI:3795835|PMID:18438409
Biological Process	GO:0045652	regulation of megakaryocyte differentiation	Mef2c	IMP		Mouse	MGI:MGI:3844189|PMID:19211936
Biological Process	GO:0043523	regulation of neuron apoptotic process	Mef2c	IMP		Mouse	MGI:MGI:5559663|PMID:22496871
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:2000310	regulation of NMDA receptor activity	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0045667	regulation of osteoblast differentiation	mef2ca	IMP		Zfish	PMID:27789622
Biological Process	GO:0060297	regulation of sarcomere organization	Mef2c	IMP		Mouse	PMID:17875930
Biological Process	GO:0051963	regulation of synapse assembly	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0060025	regulation of synaptic activity	Mef2c	IMP		Mouse	MGI:MGI:3804505|PMID:18599437
Biological Process	GO:0060025	regulation of synaptic activity	Mef2c	IMP		Mouse	MGI:MGI:5559663|PMID:22496871
Biological Process	GO:0060025	regulation of synaptic activity	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0048167	regulation of synaptic plasticity	Mef2c	IMP		Mouse	MGI:MGI:5559663|PMID:22496871
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Mef2c	IMP		Mouse	MGI:MGI:3804504|PMID:18599438
Biological Process	GO:0061333	renal tubule morphogenesis	Mef2c	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0002931	response to ischemia	Mef2c	IDA		Rat	PMID:19103177|RGD:8554846
Biological Process	GO:0031667	response to nutrient levels	Mef2c	IEP		Rat	PMID:20676734|RGD:5131607
Biological Process	GO:0033197	response to vitamin E	Mef2c	IEP		Rat	PMID:16534476|RGD:5131617
Biological Process	GO:0060021	roof of mouth development	Mef2c	IGI	MGI:MGI:101926	Mouse	PMID:17420000
Biological Process	GO:0060021	roof of mouth development	Mef2c	IGI	MGI:MGI:101927	Mouse	PMID:17420000
Biological Process	GO:0003139	secondary heart field specification	Mef2c	IMP		Mouse	MGI:MGI:3578591|PMID:15890826
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	Mef2c	IMP	MGI:MGI:2687362	Mouse	PMID:30735130
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	Mef2c	IMP	MGI:MGI:2158947	Mouse	PMID:30735130
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	Mef2c	IMP	MGI:MGI:1857637	Mouse	PMID:30735130
Biological Process	GO:0003185	sinoatrial valve morphogenesis	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724
Biological Process	GO:0035914	skeletal muscle cell differentiation	Mef2c	IMP		Mouse	PMID:22147266
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	mef2ca	IGI	ZFIN:ZDB-GENE-990415-164,ZFIN:ZDB-MRPHLNO-070730-5	Zfish	PMID:17537787
Biological Process	GO:0007519	skeletal muscle tissue development	Mef2c	IMP	MGI:MGI:3718323	Mouse	PMID:17786239
Biological Process	GO:0051145	smooth muscle cell differentiation	Mef2c	IMP	MGI:MGI:1857491	Mouse	PMID:9778514
Biological Process	GO:0097492	sympathetic neuron axon guidance	Mef2c	IMP	MGI:MGI:3718323	Mouse	PMID:30735130
Biological Process	GO:0097492	sympathetic neuron axon guidance	Mef2c	IMP	MGI:MGI:1857637	Mouse	PMID:30735130
Biological Process	GO:0097492	sympathetic neuron axon guidance	Mef2c	IMP	MGI:MGI:2687362	Mouse	PMID:30735130
Biological Process	GO:0097492	sympathetic neuron axon guidance	Mef2c	IMP	MGI:MGI:2158947	Mouse	PMID:30735130
Biological Process	GO:0060290	transdifferentiation	Mef2c	IMP		Rat	PMID:23948075|RGD:7327215
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	Mef2c	IMP		Mouse	MGI:MGI:3830899|PMID:16680724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern