Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEGF10
  • Mouse genes Megf10
  • Rat genes Megf10
  • Zfish genes megf10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Megf10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001849	complement component C1q complex binding	MEGF10	IDA		Human	PMID:27170117
Molecular Function	GO:0005112	Notch binding	MEGF10	IPI	UniProtKB:Q01705	Human	PMID:28498977
Molecular Function	GO:0005112	Notch binding	Megf10	IPI	UniProtKB:Q01705	Mouse	MGI:MGI:5902858|PMID:28498977
Molecular Function	GO:0005044	scavenger receptor activity	MEGF10	IDA		Human	PMID:27170117
Cellular Component	GO:0001891	phagocytic cup	MEGF10	IDA		Human	PMID:17205124
Cellular Component	GO:0001891	phagocytic cup	Megf10	IDA		Mouse	PMID:19915564
Cellular Component	GO:0005886	plasma membrane	MEGF10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MEGF10	IDA		Human	PMID:27170117
Cellular Component	GO:0005886	plasma membrane	Megf10	IDA		Mouse	MGI:MGI:5902858|PMID:28498977
Cellular Component	GO:0005886	plasma membrane	Megf10	IDA		Mouse	MGI:MGI:5902684|PMID:17643423
Biological Process	GO:1902742	apoptotic process involved in development	Megf10	IMP	MGI:MGI:4454190	Mouse	PMID:27170117
Biological Process	GO:0043652	engulfment of apoptotic cell	Megf10	IMP	MGI:MGI:4454190	Mouse	PMID:27170117
Biological Process	GO:0034109	homotypic cell-cell adhesion	MEGF10	IDA		Human	PMID:22407321
Biological Process	GO:0055001	muscle cell development	MEGF10	IMP		Human	PMID:22101682
Biological Process	GO:0033002	muscle cell proliferation	MEGF10	IMP		Human	PMID:28498977
Biological Process	GO:0051451	myoblast migration	MEGF10	IMP		Human	PMID:28498977
Biological Process	GO:0051451	myoblast migration	Megf10	IMP		Mouse	MGI:MGI:5902858|PMID:28498977
Biological Process	GO:0030239	myofibril assembly	megf10	IMP	ZFIN:ZDB-MRPHLNO-120504-2	Zfish	PMID:22371254
Biological Process	GO:0030239	myofibril assembly	megf10	IMP	ZFIN:ZDB-MRPHLNO-120504-1	Zfish	PMID:22371254
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	MEGF10	IMP		Human	DOI:10.1093/hmg/ddz064
Biological Process	GO:2000288	positive regulation of myoblast proliferation	MEGF10	IMP		Human	DOI:10.1093/hmg/ddz064
Biological Process	GO:0043654	recognition of apoptotic cell	Megf10	IMP		Mouse	PMID:19915564
Biological Process	GO:0043654	recognition of apoptotic cell	Megf10	IDA		Mouse	PMID:19915564
Biological Process	GO:0051147	regulation of muscle cell differentiation	MEGF10	IMP		Human	PMID:22101682
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	MEGF10	IMP		Human	PMID:22101682
Biological Process	GO:0014719	skeletal muscle satellite cell activation	Megf10	IMP		Mouse	MGI:MGI:5319607|PMID:18056409
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	MEGF10	IMP		Human	PMID:22101682
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	Megf10	IMP		Mouse	MGI:MGI:5319607|PMID:18056409
Biological Process	GO:0014841	skeletal muscle satellite cell proliferation	Megf10	IDA		Mouse	MGI:MGI:5319607|PMID:18056409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern