Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEIS3,MEIS3P1,MEIS3P2
  • Mouse genes Meis3
  • Rat genes Meis3
  • Zfish genes meis3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Meis3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Meis3	IDA		Mouse	PMID:21059917
Molecular Function	GO:0003677	DNA binding	meis3	IDA		Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Meis3	IDA		Mouse	PMID:21059917
Molecular Function	GO:0005515	protein binding	meis3	IPI	UniProtKB:Q9PW77	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Molecular Function	GO:0043565	sequence-specific DNA binding	MEIS3	IDA		Human	PMID:17178831
Molecular Function	GO:0043565	sequence-specific DNA binding	meis3	IDA		Zfish	PMID:24480644
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MEIS3	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	meis3	IDA		Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Cellular Component	GO:0005634	nucleus	Meis3	IDA		Mouse	PMID:21059917
Cellular Component	GO:0005634	nucleus	meis3	IDA		Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:0048484	enteric nervous system development	meis3	IMP	ZFIN:ZDB-MRPHLNO-080117-1	Zfish	PMID:26354419
Biological Process	GO:0031017	exocrine pancreas development	meis3	IMP	ZFIN:ZDB-MRPHLNO-080118-3	Zfish	PMID:17942484
Biological Process	GO:0030902	hindbrain development	meis3	IGI	ZFIN:ZDB-GENE-980526-290	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:0030902	hindbrain development	meis3	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Meis3	IMP		Mouse	PMID:21059917
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	meis3	IMP	ZFIN:ZDB-MRPHLNO-080117-1	Zfish	PMID:26354419
Biological Process	GO:0031016	pancreas development	meis3	IMP	ZFIN:ZDB-MRPHLNO-080117-1	Zfish	PMID:17289013
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	meis3	IGI	ZFIN:ZDB-GENE-980526-290	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	meis3	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:0035066	positive regulation of histone acetylation	meis3	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:24480644
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Meis3	IMP		Mouse	PMID:21059917
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	meis3	IGI	ZFIN:ZDB-GENE-980526-290	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	meis3	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:11262231|ZFIN:ZDB-PUB-010404-7

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern