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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Men1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Men1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingMen1IDAMousePMID:15640349
Molecular FunctionGO:0003682chromatin bindingMen1IDAMousePMID:16415155
Molecular FunctionGO:0003682chromatin bindingMen1IDAMousePMID:16195383
Molecular FunctionGO:0003682chromatin bindingMen1IDARatPMID:24157940|RGD:9589069
Molecular FunctionGO:0003677DNA bindingMen1IDAMousePMID:24824656
Molecular FunctionGO:0003677DNA bindingMen1IDAMousePMID:14992727
Molecular FunctionGO:0001216DNA-binding transcription activator activityMen1IDAMouseMGI:MGI:3035842|PMID:14992727
Molecular FunctionGO:0003690double-stranded DNA bindingMEN1IDAHumanPMID:15331604
Molecular FunctionGO:0000400four-way junction DNA bindingMEN1IDAHumanPMID:15331604
Molecular FunctionGO:0051219phosphoprotein bindingMEN1IPIUniProtKB:P24928HumanPMID:14992727
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P52651HumanPMID:11500056
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P19838HumanPMID:11526476
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P19838:PRO_0000030311HumanPMID:11526476
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q00653HumanPMID:11526476
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q04206HumanPMID:11526476
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P15927HumanPMID:12509449
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q9BXW9HumanPMID:12874027
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P35579HumanPMID:14508515
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q03164HumanPMID:14992727
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q15291HumanPMID:14992727
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q9UBL3HumanPMID:14992727
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q03164HumanPMID:15199122
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P61964HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:O00409HumanPMID:16951149
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P10242HumanPMID:20484083
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P23771HumanPMID:20484083
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:O14757HumanPMID:20969866
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q03164HumanPMID:22936661
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P17535HumanPMID:23784080
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P61964HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:Q03164HumanPMID:25305204
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P61964HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P17535HumanPMID:9989505
Molecular FunctionGO:0005515protein bindingMEN1IPIUniProtKB:P61604HumanPMID:9989505
Molecular FunctionGO:0005515protein bindingMen1IPIUniProtKB:Q9Z0Y9MouseMGI:MGI:5695430|PMID:25962847
Molecular FunctionGO:0005515protein bindingMen1IPIUniProtKB:P23204MouseMGI:MGI:5295314|PMID:22001208
Molecular FunctionGO:0005515protein bindingMen1IPIPR:P70340MousePMID:15150273
Molecular FunctionGO:0005515protein bindingMen1IPIPR:Q8BUN5MousePMID:15150273
Molecular FunctionGO:0005515protein bindingMen1IPIPR:Q08775MousePMID:15150273
Molecular FunctionGO:0005515protein bindingMen1IPIPR:P97454MousePMID:15150273
Molecular FunctionGO:0005515protein bindingMen1IPIPR:P55200MousePMID:16618927
Molecular FunctionGO:0005515protein bindingmen1IPIUniProtKB:P17535ZfishPMID:10818209
Molecular FunctionGO:0030674protein-macromolecule adaptor activityMEN1IDAHumanPMID:20484083
Molecular FunctionGO:0070412R-SMAD bindingMEN1IPIUniProtKB:P84022HumanPMID:11274402
Molecular FunctionGO:0043565sequence-specific DNA bindingMen1IDAMousePMID:20956546
Molecular FunctionGO:0000976transcription cis-regulatory region bindingMEN1IDAHumanPMID:20484083
Molecular FunctionGO:0000976transcription cis-regulatory region bindingMen1IDAMouseMGI:MGI:3035842|PMID:14992727
Molecular FunctionGO:0000403Y-form DNA bindingMEN1IDAHumanPMID:15331604
Cellular ComponentGO:0000785chromatinMEN1IDAHumanPMID:12837246
Cellular ComponentGO:0000785chromatinMEN1IDAHumanPMID:12874027
Cellular ComponentGO:0000781chromosome, telomeric regionMen1IDAMouseMGI:MGI:5751680|PMID:12203793
Cellular ComponentGO:0032154cleavage furrowMEN1IDAHumanPMID:14508515
Cellular ComponentGO:0005737cytoplasmMEN1IDAHumanPMID:11500056
Cellular ComponentGO:0005737cytoplasmMen1IDAMousePMID:9824159
Cellular ComponentGO:0005829cytosolMEN1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005829cytosolMEN1IDAHumanPMID:14508515
Cellular ComponentGO:0035097histone methyltransferase complexMEN1IDAHumanPMID:17500065
Cellular ComponentGO:0071339MLL1 complexMEN1IPIHumanPMID:23508102
Cellular ComponentGO:0044665MLL1/2 complexMEN1IPIHumanPMID:23508102
Cellular ComponentGO:0016363nuclear matrixMEN1IDAHumanPMID:12874027
Cellular ComponentGO:0005654nucleoplasmMEN1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusMEN1IDAHumanPMID:14508515
Cellular ComponentGO:0005634nucleusMEN1IDAHumanPMID:15199122
Cellular ComponentGO:0005634nucleusMEN1IDAHumanPMID:15640349
Cellular ComponentGO:0005634nucleusMEN1IDAHumanPMID:17500065
Cellular ComponentGO:0005634nucleusMEN1IDAHumanPMID:9465067
Cellular ComponentGO:0005634nucleusMen1IDAMousePMID:17044021
Cellular ComponentGO:0005634nucleusMen1IDAMousePMID:9824159
Cellular ComponentGO:0005634nucleusMen1IDAMousePMID:15150273
Cellular ComponentGO:0005634nucleusMen1IDAMousePMID:12941803
Cellular ComponentGO:0005634nucleusMen1IDAMousePMID:16195383
Cellular ComponentGO:0005634nucleusMen1IDARatPMID:10612420|RGD:69890
Cellular ComponentGO:0032991protein-containing complexMEN1IDAHumanPMID:15199122
Cellular ComponentGO:0017053transcription repressor complexMEN1IPIHumanPMID:22327296
Biological ProcessGO:0007420brain developmentMen1IEPRatPMID:10612420|RGD:69890
Biological ProcessGO:0051301cell divisionMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:0051301cell divisionMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:2683274,MGI:MGI:2683304MousePMID:14633735
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0008283cell population proliferationMen1IGIMGI:MGI:105388MousePMID:17409423
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:2176227,MGI:MGI:2384620MousePMID:15060136
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:2387567,MGI:MGI:2675250MousePMID:12941803
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0008283cell population proliferationMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:0008283cell population proliferationMen1IDAMousePMID:17975067
Biological ProcessGO:0071333cellular response to glucose stimulusMen1IEPRatPMID:22166975|RGD:9589127
Biological ProcessGO:0071375cellular response to peptide hormone stimulusMen1IEPRatPMID:21239441|RGD:9589145
Biological ProcessGO:0006338chromatin remodelingMen1IMPMGI:MGI:2158698MousePMID:15044367
Biological ProcessGO:0006338chromatin remodelingMen1IGIMGI:MGI:88393MousePMID:16415155
Biological ProcessGO:0046697decidualizationMen1IEPRatPMID:19780023|RGD:9589138
Biological ProcessGO:0006974DNA damage responseMEN1IDAHumanPMID:16690369
Biological ProcessGO:0009790embryo developmentMen1IMPMGI:MGI:2158698MousePMID:11158604
Biological ProcessGO:0048704embryonic skeletal system morphogenesisMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0044346fibroblast apoptotic processMen1IGIMGI:MGI:99702MousePMID:14688275
Biological ProcessGO:0044346fibroblast apoptotic processMen1IDAMousePMID:14688275
Biological ProcessGO:0044346fibroblast apoptotic processMen1IGIMGI:MGI:1097161MousePMID:14688275
Biological ProcessGO:0048144fibroblast proliferationMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0048144fibroblast proliferationMen1IMPMousePMID:15640349
Biological ProcessGO:0030097hemopoiesisMen1IMPMGI:MGI:2158697MousePMID:16415155
Biological ProcessGO:0001776leukocyte homeostasisMen1IMPMGI:MGI:2158697MousePMID:16415155
Biological ProcessGO:0000165MAPK cascadeMEN1IDAHumanPMID:12226747
Biological ProcessGO:0060135maternal process involved in female pregnancyMen1IDAMousePMID:17975067
Biological ProcessGO:0000278mitotic cell cycleMen1IEPRatPMID:10537281|RGD:2317358
Biological ProcessGO:0045786negative regulation of cell cycleMEN1IDAHumanPMID:15331604
Biological ProcessGO:1902807negative regulation of cell cycle G1/S phase transitionMen1IMPRatPMID:15054094|RGD:1304318
Biological ProcessGO:0008285negative regulation of cell population proliferationMEN1IDAHumanPMID:15331604
Biological ProcessGO:0008285negative regulation of cell population proliferationMen1IMPMGI:MGI:2683274,MGI:MGI:2683304MousePMID:14633735
Biological ProcessGO:0008285negative regulation of cell population proliferationMen1IMPMGI:MGI:2158698MousePMID:11158604
Biological ProcessGO:0008285negative regulation of cell population proliferationMen1IDAMousePMID:15044367
Biological ProcessGO:0008285negative regulation of cell population proliferationMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0010812negative regulation of cell-substrate adhesionMen1IMPRatPMID:15054094|RGD:1304318
Biological ProcessGO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityMEN1IMPHumanPMID:15640349
Biological ProcessGO:0043433negative regulation of DNA-binding transcription factor activityMEN1IDAHumanPMID:11526476
Biological ProcessGO:0043433negative regulation of DNA-binding transcription factor activityMEN1IDAHumanPMID:12226747
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionMEN1IDAHumanPMID:12226747
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionmen1IDAZfishPMID:10818209
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationMen1IMPRatPMID:15054094|RGD:1304318
Biological ProcessGO:0048147negative regulation of fibroblast proliferationMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0048147negative regulation of fibroblast proliferationMen1IMPMousePMID:15640349
Biological ProcessGO:0046329negative regulation of JNK cascadeMEN1IDAHumanPMID:12226747
Biological ProcessGO:0046621negative regulation of organ growthMen1IDAMousePMID:17975067
Biological ProcessGO:0045668negative regulation of osteoblast differentiationMEN1IGIMGI:MGI:1316736HumanPMID:15563473
Biological ProcessGO:0045668negative regulation of osteoblast differentiationMen1IDAMousePMID:15150273
Biological ProcessGO:0045668negative regulation of osteoblast differentiationMen1IGIMGI:MGI:96648MousePMID:15563473
Biological ProcessGO:0001933negative regulation of protein phosphorylationMEN1IDAHumanPMID:12226747
Biological ProcessGO:2000647negative regulation of stem cell proliferationMen1IGIMGI:MGI:105388MousePMID:17409423
Biological ProcessGO:2000647negative regulation of stem cell proliferationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0051974negative regulation of telomerase activityMEN1IMPHumanPMID:12837246
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMEN1IDAHumanPMID:12837246
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMEN1IDAHumanPMID:22327296
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMEN1IDAHumanPMID:23784080
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMEN1IDAHumanPMID:9989505
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMen1IDAMousePMID:15044367
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIMen1IMPRatPMID:22120711|RGD:9589134
Biological ProcessGO:1904691negative regulation of type B pancreatic cell proliferationMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:1904691negative regulation of type B pancreatic cell proliferationMen1IDAMousePMID:17975067
Biological ProcessGO:1904691negative regulation of type B pancreatic cell proliferationMen1IMPMGI:MGI:2387567,MGI:MGI:2675250MousePMID:12941803
Biological ProcessGO:1904691negative regulation of type B pancreatic cell proliferationMen1IMPMGI:MGI:2176227,MGI:MGI:2384620MousePMID:15060136
Biological ProcessGO:0035265organ growthMen1IDAMousePMID:17975067
Biological ProcessGO:0001503ossificationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0002076osteoblast developmentMEN1IGIMGI:MGI:1316736HumanPMID:15563473
Biological ProcessGO:0002076osteoblast developmentMen1IGIMGI:MGI:96648MousePMID:15563473
Biological ProcessGO:0002076osteoblast developmentMen1IGIMGI:MGI:1201674MousePMID:15150273
Biological ProcessGO:0002051osteoblast fate commitmentMen1IGIMGI:MGI:99829MousePMID:15150273
Biological ProcessGO:0002051osteoblast fate commitmentMen1IGIMGI:MGI:109452MousePMID:15150273
Biological ProcessGO:0002051osteoblast fate commitmentMen1IGIMGI:MGI:1328787MousePMID:15150273
Biological ProcessGO:0051781positive regulation of cell divisionMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0051781positive regulation of cell divisionMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic processMen1IDAMousePMID:14688275
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionMen1IDAMousePMID:14992727
Biological ProcessGO:2000271positive regulation of fibroblast apoptotic processMen1IDAMousePMID:14688275
Biological ProcessGO:2000271positive regulation of fibroblast apoptotic processMen1IGIMGI:MGI:1097161MousePMID:14688275
Biological ProcessGO:2000271positive regulation of fibroblast apoptotic processMen1IGIMGI:MGI:99702MousePMID:14688275
Biological ProcessGO:0010628positive regulation of gene expressionMen1IMPMousePMID:24824656
Biological ProcessGO:0010628positive regulation of gene expressionMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:0010628positive regulation of gene expressionMen1IDAMousePMID:14992727
Biological ProcessGO:0010628positive regulation of gene expressionMen1IMPMGI:MGI:2158697MousePMID:16415155
Biological ProcessGO:0010628positive regulation of gene expressionMen1IDAMousePMID:24824656
Biological ProcessGO:0045669positive regulation of osteoblast differentiationMen1IGIMGI:MGI:88177MousePMID:15150273
Biological ProcessGO:2000738positive regulation of stem cell differentiationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMEN1IMPHumanPMID:15199122
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IMPMGI:MGI:2158698MousePMID:20956546
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IMPMGI:MGI:2158697MousePMID:16415155
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IDAMousePMID:16195383
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IGIMGI:MGI:99829MousePMID:15150273
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IGIMGI:MGI:1201674MousePMID:15150273
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IGIMGI:MGI:96995MousePMID:15640349
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIMen1IMPRatPMID:24157940|RGD:9589069
Biological ProcessGO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayMEN1IMPHumanPMID:11274402
Biological ProcessGO:0032925regulation of activin receptor signaling pathwayMen1IMPRatPMID:15031321|RGD:2290185
Biological ProcessGO:2000045regulation of G1/S transition of mitotic cell cycleMen1IMPMGI:MGI:2158697,MGI:MGI:3663673MousePMID:16740708
Biological ProcessGO:0010468regulation of gene expressionMen1IDAMousePMID:24824656
Biological ProcessGO:0061469regulation of type B pancreatic cell proliferationMen1IMPRatPMID:24157940|RGD:9589069
Biological ProcessGO:0010332response to gamma radiationMEN1IDAHumanPMID:12874027
Biological ProcessGO:0071559response to transforming growth factor betaMen1IMPRatPMID:15054094|RGD:1304318
Biological ProcessGO:0009411response to UVMEN1IDAHumanPMID:16690369
Biological ProcessGO:0060021roof of mouth developmentMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0048863stem cell differentiationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0072089stem cell proliferationMen1IMPMGI:MGI:2683274,MGI:MGI:3573783MousePMID:17927973
Biological ProcessGO:0072089stem cell proliferationMen1IGIMGI:MGI:105388MousePMID:17409423
Biological ProcessGO:0045064T-helper 2 cell differentiationMEN1IDAHumanPMID:20484083
Biological ProcessGO:0045815transcription initiation-coupled chromatin remodelingMEN1IMPHumanPMID:14992727
Biological ProcessGO:0045815transcription initiation-coupled chromatin remodelingMen1IMPMouseMGI:MGI:3035842|PMID:14992727
Biological ProcessGO:0003309type B pancreatic cell differentiationMen1IMPRatPMID:24157940|RGD:9589069
Biological ProcessGO:0044342type B pancreatic cell proliferationMen1IMPMGI:MGI:2387567,MGI:MGI:2675250MousePMID:12941803
Biological ProcessGO:0044342type B pancreatic cell proliferationMen1IMPMGI:MGI:3608952MousePMID:16195383
Biological ProcessGO:0044342type B pancreatic cell proliferationMen1IDAMousePMID:17975067
Biological ProcessGO:0044342type B pancreatic cell proliferationMen1IMPMGI:MGI:2176227,MGI:MGI:2384620MousePMID:15060136

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory